Antimicrobial natural product active against both MRSA and malaria causing parasite

The development of new active substances against pathogenic bacteria, parasites, fungi and viruses is gaining importance, as established anti-infectives are becoming increasingly ineffective due to the development of resistance. At the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), a team led by Prof Rolf Müller has optimized an antimicrobial natural product that is active against infections with both the hospital acquired MRSA pathogen and the malaria causing parasite, for preclinical research and future potential application in humans. The researchers have published their results in the journal Angewandte Chemie International Edition.