Dual Intrinsic And Extrinsic Control Of Stem Cell Aging Demonstrated

It is widely postulated that a decrease in the number and activity of stem cells contributes to the aging of human tissue. These changes could be fundamental to many symptoms of aging such as wrinkling of skin and decreased organ function. The control of stem cell aging has, until now, been poorly understood, but now scientists have demonstrated that specific factors are associated with an age-dependent decline in the function of stem cells and their microenvironment, called a niche.