- ScienceDaily
- 19/10/31 22:47
A phase three clinical trial determined that a 3-drug combination improved lung function and reduced symptoms in cystic fibrosis (CF) patients who have a single copy of the most common genetic mutation for the disease.
A phase three clinical trial determined that a 3-drug combination improved lung function and reduced symptoms in cystic fibrosis (CF) patients who have a single copy of the most common genetic mutation for the disease.
Scientists are using simple peptides to deliver gene-editing tools into notoriously hard-to-access lung and airway cells with the goal of creating new treatments for people with diseases like cystic fibrosis, COPD, and asthma.
'PollyO' is a new hazelnut variety from the Oregon State University Breeding Program that combines a high level of resistance to eastern filbert fungal blight along with high nut yield.
Researchers have developed a way to map strain in lead halide perovskite solar cells without harming them. Their approach can image the grain structure of a perovskite solar cell, showing that misorientation between microscopic perovskite crystals is the primary contributor to the buildup of strain within the solar cell. Crystal misorientation creates small-scale defects in the grain structure,...
A new study illustrates that the brain's cerebrospinal fluid pulses during sleep, and that these motions are closely tied with brain wave activity and blood flow. It may confirm the hypothesis that CSF flow and slow-wave activity both help flush toxic, memory-impairing proteins from the brain.
Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidating how the RSC complex works and what role it has in healthy and cancer cells.
Paleontologists have used modern tools to identify the origins of a few fragments of teeth found more than four decades ago by a schoolteacher in the Yukon.
Little is known about the molecular and cellular events that occur during early embryonic development in primate species. Now, scientists have created a method to allow primate embryos to grow in the laboratory longer than ever before, enabling the researchers to obtain molecular details of key developmental processes for the first time. This research, while done in nonhuman primate cells, can...
Researchers investigated a recently discovered feat carried out by enzymes, and most likely, all proteins. Under proper conditions, they can act as superb conductors of electricity, permitting them to be incorporated into a range of electronic devices.
New research shows that astronomers' search for black holes might have been missing an entire class of black holes that they didn't know existed. Astronomers offer a new way to search for black holes, and show that it is possible there is a class of black holes smaller than the smallest known black holes in the universe.
The origin of the universe started with the Big Bang, but how the supernova explosion ignited has long been a mystery -- until now.
'Smoker's Face,' a condition where smokers look older than they are, is just one of many negative effects caused by heavy tobacco usage.
A new study gives pause to the idea of using oil and gas wastewater for irrigation. The team conducted a greenhouse study using produced water to irrigate common wheat crops. Their study showed that these crops had weakened immune systems.
One third of all approved drugs target the same family of receptors: the G-Protein-Coupled Receptors (GPCRs). Now, researchers have expanded the known network of peptides that activate GPCRs by 19 percent.
Researchers have gained tantalizing new insights into the properties of perovskites, one of the world's most promising materials in the quest to produce a more efficient, robust and cheaper solar cell.
Consumers were more willing to buy unlabeled produce after being shown food tagged as ''genetically modified'' in a new study that comes two months before a new federal law, requiring genetically modified organism disclosure labels on food products, goes into effect.
Bioscientists find a way to predict the sensitivity of acute myeloid leukemia to mitochondria-damaging molecules and develop cocktails to fight the cancer. The discoveries could improve personalized cancer treatment.
It can take years of birdwatching experience to tell one species from the next. But using an artificial intelligence technique called deep learning, researchers have trained a computer to identify up to 200 species of birds from just a photo. This tool goes beyond giving the right answer to explain its thinking, in a way that even someone who doesn't know a penguin from a puffin can understand.
Researchers created a mutated version of RAD51, a DNA repair protein, to better understand its critical functions at key steps in the cell replication process during times of stress. This work may help cancer biology scientists better understand how cells protect DNA from damage during replication. Defects in this pathway may play a role in causing cancer and a better understanding of the process...
During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists have now identified a protein that regulates the growth of these extensions by pulling a brake. In the long run, their findings could help to develop new approaches for the treatment of spinal cord injuries.
Researchers unravel novel dynamics in the interaction between light and mechanical motion with significant implications for quantum measurements designed to evade the influence of the detector in the notorious 'back action limit' problem.
Scientists model how the 'weather' on a star impacts exoplanets to see if even those thought to be in habitable zones could suffer from solar storms. They expect their work to help narrow the number of exoplanets studied for their potential to harbor life.
A new study uses a special genetic sequencing technique known as low-pass genome sequencing (GS) to look for chromosomal abnormalities in couples with RM. Low-pass GS revealed additional chromosomal abnormalities in more couples than traditional testing, increasing detection to 1 in 9 couples.
Stem cells of the teeth can contribute to the regeneration of non-dental organs, namely mammary glands. According to a new study, dental epithelial stem cells from mice can generate mammary ducts and even milk-producing cells when transplanted into mammary glands. This could be used for post-surgery tissue regeneration in breast cancer patients.
Vampire bats that share food and groom each other in captivity are more likely to stick together when they're released back into the wild, find researchers. While most previous evidence of 'friendship' in animals comes from research in primates, these findings suggest that vampire bats can also form cooperative, friendship-like social relationships.