feed info

8 articles from ScienceDaily

Breathing new life into the rise of oxygen debate

New research strongly suggests that the distinct 'oxygenation events' that created Earth's breathable atmosphere happened spontaneously, rather than being a consequence of biological or tectonic revolutions. The study not only shines a light on the history of oxygen on our planet, it gives new insight into the prevalence of oxygenated worlds other than our own.

Genetic brain disorder fixed in mice using precision epigenome editing

Using a targeted gene epigenome editing approach in the developing mouse brain, researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, which causes intellectual disability and obesity in people. This specific editing was unique in that it changed the epigenome -- how the genes are regulated -- without changing the actual genetic code of the gene being regulated.

Regional trends in overdose deaths reveal multiple opioid epidemics

The United States in the grip of several simultaneously occurring opioid epidemics, rather than just a single crisis. The epidemics came to light after the researchers analyzed county-level data on drug overdose deaths. The study highlights the importance of different policy responses to the epidemics rather than a single set of policies.

Alzheimer's drug candidates reverse broader aging, study shows

In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, researchers have shown how these compounds can also slow aging in healthy older mice, blocking the damage to brain cells that normally occurs during aging and restoring the levels of specific molecules to those seen in younger brains.