342 articles from THURSDAY 16.1.2020

A secreted signature of aging cells

Senescent cells undergo an irreversible and permanent arrest of cell division and are hallmarks of both the aging process and multiple chronic diseases. Senescent cells -- and more importantly the factors they secrete, known collectively as the senescence-associated secretory phenotype (SASP) -- are widely accepted as drivers of aging and multiple age-related diseases.

Efficacy of drugs against pork tapeworm

Taenia solium -- also called pork tapeworm -- is a parasite which causes disease around the world, particularly in very poor communities with deficient sanitation and where pigs roam free. Researchers have now analyzed the efficacy and adverse effects of three chemotherapeutics against T. solium.

Mosquitoes engineered to repel dengue virus

Scientists have synthetically engineered mosquitoes that halt the transmission of the dengue virus. Biologists developed a human antibody for dengue suppression in Aedes aegypti mosquitoes, the insects that spread dengue. The development marks the first engineered approach in mosquitoes that targets the four known types of dengue, improving upon previous designs that addressed single strains.