- EurekAlert
- 20/10/23 06:00
Researchers uncover defining features of a subset of T-cells that may drive autoimmunity in MS, and could prove to be a new target for therapy.
199 articles from FRIDAY 23.10.2020
Researchers uncover defining features of a subset of T-cells that may drive autoimmunity in MS, and could prove to be a new target for therapy.
A team led by an astronomer from the University of Kansas has crunched data from NASA's TESS and Spitzer space telescopes to portray for the first time the atmosphere of a highly unusual kind of exoplanet dubbed a 'hot Neptune.'
Recent successes of several FDA-approved therapeutic nucleic acids, together with the rapid preclinical progression of nucleic acid nanoparticles (NANPs), have made it apparent that immunological effects of NANPs must be carefully assessed to permit their successful clinical translation. Based on extensive studies, a standardized protocol allowing for the assessment of NANPs' pro-inflammatory...
Using an RNA molecule complex, researchers can prevent retention of cancer stem cell in their tumor supporting niche
Using two mode-locked femtosecond lasers and a single photon counting detector, scientists have recorded broad spectra with close to one hundred thousand colors in almost complete darkness.
Oncotarget recently published "A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo which reported that here, the authors describe four novel formats for the L19-IL2 fusion, featuring different arrangements of antibody and IL2.
The plant compound apigenin improved the cognitive and memory deficits usually seen in a mouse model of Down syndrome, according to a study by researchers at the National Institutes of Health and other institutions. Apigenin is found in chamomile flowers, parsley, celery, peppermint and citrus fruits. The findings raise the possibility that a treatment to lessen the cognitive deficits seen in Down...
A study, published in PLOS ONE, found that the women living in Dhaka slums were reluctant to use institutionalised maternal health care for fear of having to make undocumented payments, unfamiliar institutional processes, lack of social and family support, matters of honour and shame, a culture of silence and inadequate spousal communication on health issues.
Stress is present everywhere, even bacteria and plant cells have to cope with it. They express various specific stress proteins, but how exactly this line of defense works is often not clear. A group of scientists headed by Professor Dirk Schneider of Johannes Gutenberg University Mainz (JGU) has now discovered a protective mechanism in cyanobacteria as well as in chloroplasts of plant cells.
Through intricate experiments designed to account for sex-specific differences, scientists at Scripps Research have collaborated to zero-in on certain changes in the brain that may be responsible for driving alcohol abuse among people with PTSD. In studies with rodents, researchers found that males and females exhibit their own distinct symptoms and brain features of PTSD and alcohol use disorder....
Based on a quantum cascade laser (QCL) emitting mid-infrared light, the researchers developed a basic optical neuron system operating 10,000Ã faster than biological neurons. Their report is published in Advanced Photonics.
A study quantified the size and age of the forests that grow naturally in degraded and abandoned areas, creating 131 benchmark maps for Brazil. The Amazon has the most restored forests and the Atlantic Rainforest biome has the oldest.
Moving around in the half-light is difficult but not impossible. To help us in this undertaking we have the rods, a type of photoreceptors present in the retina of vertebrates, capable of detecting very low lights. They are the protagonists of the new study published in PNAS by a team of researchers of SISSA and CNR-Iom which reveals new and essential details of how the retina works and in...
What about the kidneys make them a hotspot for COVID-19's cytokine storm? A research team says it's the presence of a protein found on specialized renal transport cells.
For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as stem cells of the airways because they can regenerate the airway epithelium in response to injury, this study may help accelerate research on diseases impacting the airway,...
Researchers have discovered a gene that is critical for the development of Ewing sarcoma, a rare type of developmental cancer that presents in bones and soft tissues. Exploring the pharmacological inhibition of RING1B as a clinical therapy to treat Ewing sarcoma could open the door for new treatments for the rare disease.
Residents of U.S. counties with more social connections (measured as Facebook friends) to China or Italy - the first countries to report major COVID-19 outbreaks - were more likely to adhere to social distancing restrictions at the onset of the pandemic, according to a new study.
Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not.
N-heterocycles are organic substances used in the chemical industry and medicine. To produce them, expensive catalysts made from noble metals are used. A chemist from RUDN University developed a nanocatalyst for N-heterocycles that consists of zinc oxide and niobium and can be obtained using orange peel without any additional chemical agents. The catalyst makes the reaction almost 100% effective,...
A new study led by Marc Veldhoen, principal investigator at Instituto de Medicina Molecular with an interdisciplinary team of clinicians and researchers from FMUL and CHLN and collaborators at IPST, shows that 90% of subjects have detectable antibodies 40 days up to 7 months post contracting COVID-19. These results, now published in the scientific journal European Journal of Immunology, also show...
Researchers at National University of Science and Technology MISIS (NUST MISIS) have managed to develop a unique method to process bulk metallic glasses. According to the authors of the study, they have managed to find processing conditions that significantly improve the quality of this promising material. The research results were published in Journal of Alloys and Compounds.
A 14,000-year paleoecological reconstruction of the sub-Antarctic islands led by University of Maine researchers has found that seabird establishment occurred during a period of regional cooling 5,000 years ago. Their populations, in turn, shifted the Falkland Islands ecosystems through the deposit of high concentrations of guano that helped nourish tussac, produce peat and increase the incidence...
This study examined the seropositive prevalence of antibodies against SARS-CoV-2 in Wuhan, China, by sex and age group.
Researchers develop a new method to isolate specific cells, and in the process find a more robust fluorescent protein.
ALMA shows rings around the still-growing proto-star IRS 63