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86 articles from ScienceDaily

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries a genetic messenger (messenger...

Surprises in 'active' aging

Aging is a process that affects not only living beings. Many materials, like plastics and glasses, also age -- ie they change slowly as their particles try to pack better. Biological materials, such as living tissue, show similar behavior to glasses except that the particles are actual cells with their own propulsion. Researchers used computer simulations to explore the aging behavior of these...

Algae breathe life into 3D engineered tissues

3D bioprinted algae can be harnessed as a sustainable source of oxygen for human cells in engineered vascularized tissues, researchers report. They embedded the bioprinted photosynthetic algae, along with human liver-derived cells, in a 3D hydrogel matrix to create honeycomb-shaped tissues with lobules, similar to the human liver.

Novel magnetic spray transforms objects into millirobots for biomedical applications

An easy way to make millirobots by coating objects with a glue-like magnetic spray has been developed. Driven by the magnetic field, the coated objects can crawl, walk, or roll on different surfaces. As the magnetic coating is biocompatible and can be disintegrated into powders when needed, this technology demonstrates the potential for biomedical applications, including catheter navigation and...

Vertebrate biodiversity: A glimmer of hope

A team of biologists found that the picture of dramatically declining vertebrate populations of all kinds is driven by a small number of outlier populations whose numbers are dropping at extreme rates. Once these outliers are separated from the mix, a very different and far more hopeful picture of global biodiversity emerges.

Gut microbiome manipulation could result from virus discovery

Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells - a finding that could be used to control the composition of the gut microbiome, which is important for human health. The research could aid efforts to engineer beneficial bacteria that produce medicines and fuels and clean up pollutants.

Versatile building blocks make structures with surprising mechanical properties

Researchers have created tiny building blocks that exhibit unique mechanical properties, such as the ability to produce a twisting motion when squeezed. These subunits could potentially be assembled by robots into a nearly limitless variety of objects with built-in functionality, including vehicles, large industrial parts, or specialized robots that can be repeatedly reassembled in different...

Fostering creativity in researchers: How automation can revolutionize materials research

Scientists have devised a system that combines robotics and artificial intelligence to fully automate the routine aspects of synthesizing, testing, and optimizing new materials according to fabrication conditions. Their approach can produce and test compounds ten times faster than scientists doing manual work, allowing for the rapid creation of huge shared databases. In turn, the autonomous system...

Unraveling a mystery surrounding embryonic cells

Last year, researchers identified the early origins of neural crest cells -- embryonic cells in vertebrates that travel throughout the body and generate many cell types -- in chick embryos. Now the researchers have used a human model to figure out when neural crest cells acquire distinctive molecular and functional attributes.

Brain protein could be starting point for new treatments for pancreatic cancer

Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer. Their findings demonstrate for the first time how the protein, called Netrin-G1, helps pancreatic cancer cells survive by protecting them from the immune system and supplying them with nutrients.