Molecular tweezers that attack antibiotic resistant bacteria developed by Ben-Gurion U.
319 articles from MONDAY 10.5.2021
Monash study may help boost peptide design
Prof. Jelinek, who is also BGUs vice president of Research & Development and a member of the Ilse Katz Institute for Nanoscale Science and Technology explained, "The tweezers are just like your home tweezers but a million times smaller, and instead of plucking hairs they attack fibers of the bacteria's biofilm." By doing that they break the biofilm, making it more vulnerable to human immune...
Mount Sinai ophthalmologists develop new technique to assess progression of sickle cell retinopathy
Peptides play a vital role with a huge range of medical uses including in antibiotics and anti-cancer drugs. Altering the structure of natural peptides to improve compounds is of great interest to scientists and industry. But how these peptides are produced still isn't clearly understood. Monash University researchers have revealed a key aspect of peptide machineries in a paper published in...
New finding suggests cognitive problems caused by repeat mild head hits could be treated
Breakthrough technology may help prevent vision loss and understand effectiveness of therapy.
New mapping technique reveals epigenetic drivers of cancers
A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified. The finding suggests that tailored drug therapy can be designed and developed to reactivate and normalize cognitive function, say neuroscientists at Georgetown University Medical Center.
New study finds an association between increasing BMI and the risk of testing positive for SARS-CoV-2
Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a similar effect.
New theory may revolutionize treatment of endometriosis
New research presented at this year's European Congress on Obesity (held online, 10-13 May) reveals an association between increasing body mass index (BMI) and the risk of testing positive SARS-CoV-2, the virus which causes COVID-19. The study is by Dr Hadar Milloh-Raz, The Chaim Sheba Medical Center, Tel-HaShomer, Ramat-Gan, Israel, and colleagues.
New tools enable rapid analysis of coronavirus sequences and tracking of variants
Endometriosis, a disease found in up to 10 per cent of women, has been enigmatic since it was first described. A new theory developed by researchers at Simon Fraser University suggests a previously overlooked hormone -- testosterone -- has a critical role in its development. The research could have direct impacts on diagnosis and treatment of the disease, signaling hope for women with...
New vaccine blocks COVID-19 and variants, plus other coronaviruses
Widespread sequencing of SARS-CoV-2 genomes presents new opportunities for tracing global and local transmission dynamics, but analyzing so much genomic data is challenging. The sheer number of coronavirus genome sequences and their rapid accumulation makes it hard to place new sequences on a "family tree" showing how they are all related. But researchers at the UC Santa Cruz Genomics Institute...
Of mice and spacemen: Understanding muscle wasting at the molecular level
A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.
Older adults having surgery less frequently -- but it depends on the surgery and hospital
Skeletal muscles undergo atrophy, or wasting, under conditions of reduced gravity, such as during spaceflight. Researchers from the University of Tsukuba explored the effects of microgravity and artificial gravity (1 g) on mice housed at the International Space Station for 35 days. Artificial gravity successfully prevented the gross and molecular changes observed in the muscles of mice subjected...
Once we're past the fear stage, where do we place the blame for the COVID-19 pandemic?
Contrary to popular belief, a new study from the University of Chicago Medicine found the frequency of abdominal surgery in older adults is decreasing, especially among adults over the age of 85.
One-year results from the FUTURE-II trial
In a recent study, conducted in Poland in 2020 and published in the peer-reviewed journal Social Psychological Bulletin, scientists concluded it was the government and the system that most of the participants attributed responsibility to for the COVID-19 incidence rates. Furthermore, political views and party preferences are reported to play an incomparably more significant role in their responses...
Parallel universes cross in Flatland
A decade already passed from the first use of bioresorbable vascular scaffold in percutaneous coronary interventions. The first studies - by using surrogate endpoints - showed some superiority of BRS vs. metallic drug-eluting stent in terms of the so-called vascular restoration therapy with recovery of vasomotion and vascular pulsatility when the scaffold was absorbed....
Peers who boost marginalized voices help others, and themselves, study shows
Physics researchers at the University of Bath discover that assembling 2D materials into a 3D arrangement does not just result in 'thicker' 2D materials but instead produces entirely new materials. The nanomesh technologically pioneered at Bath is simple to produce and offers tunable material properties to meet the demands of future applications. The team's next goal is to use the nanomesh on...
Point-of-care ultrasonography offers enormous advantages in acute diagnostics
New research from the University of Notre Dame is the first to show that peers can help boost marginalized voices, and at the same time benefit their own status, all while helping their organization realize the potential of its employees' diverse perspectives.
Prenatal exposure to famine heightens risk for later being overweight
Point-of-Care UltraSonography deployed during the emergency treatment of patients with acute dyspnea has enormous advantages over standard diagnostic pathways. This is the finding of a joint review conducted by Danube University Krems and MedUni Vienna and recently published in the prestigious Annals of Internal Medicine. It allows serious conditions to be identified more quickly so that...
Rapid lifestyle changes during early COVID-19 pandemic had no impact on climate change
An analysis of historical medical records found that men who were prenatally exposed during early gestation to the Dutch famine of 1944-1945 were 30 percent more likely to be overweight with a Body Mass Index of 25 or over at age 19, compared to a similar group not exposed to the famine.
Reaching your life goals as a single-celled organism
Despite the rapid and significant changes in consumption patterns witnessed during the initial months of the COVID-19 pandemic, Japanese households maintained their normal levels of greenhouse gases emissions. The "anthropause" -- reduction of human activity due to the pandemic -- made headlines last summer, but factory shutdowns and broken global supply chains did not translate into the adoption...
Recycling critical metals in e-waste: Make it the law, experts warn EU, citing raw material security
How is it possible to move in the desired direction without a brain or nervous system? Single-celled organisms apparently manage this feat without any problems: for example, they can swim towards food with the help of small flagellar tails. A research team at TU Wien (Vienna) has now been able to simulate this process on the computer.
Research results challenge a decades-old mechanism of how we hear sounds
End-of-life circuit boards, certain magnets in disc drives and electric vehicles, EV and other special battery types, and fluorescent lamps are among several electrical and electronic products containing critical raw materials (CRMs), the recycling of which should be made law, says a new UN-backed report funded by the EU.
Research shows opportunities to improve the accuracy of dispatching pre-hospital critical care
Researchers at LinkÃ¶ping University, Sweden, have made several discoveries on the functioning mechanisms of the inner hair cells of the ear, which convert sounds into nerve signals that are processed in the brain. The results, presented in the scientific journal Nature Communications, challenge the current picture of the anatomical organisation and workings of the hearing organ, which has...
Researchers achieve 50dB noiseless at all optical isolation
Research from life-saving charity Air Ambulance Kent Surrey Sussex (KSS) and the University of Surrey indicates that the criteria for immediate Helicopter Emergency Medical Services (HEMS) dispatch to older trauma patients should be reviewed.
Researchers in Sweden develop light emitters for quantum circuits
Chinese researchers achieved 51.5dB nonreciprocal isolation in the atomic ensemble, which is the highest isolation ratio in the non-magnetic nonreciprocal field.
Researchers use arcuate organoids to study development and disease of the hypothalamus
The promise of a quantum internet depends on the complexities of harnessing light to transmit quantum information over fiber optic networks. A potential step forward was reported today by researchers in Sweden who developed integrated chips that can generate light particles on demand and without the need for extreme refrigeration.
For the first time, researchers at Penn Medicine created organoids of the arcuate nucleus (ARC),providing an atlas of cell types in the human hypothalamus, which will be a blueprint to further understanding the development of brain disorders, such as certain causes of obesity and autism.