319 articles from MONDAY 10.5.2021
CDK inhibitors may improve immune therapy effectiveness for recurrent breast cancer
A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by researchers atThe Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.
CHEST releases updated guidelines to diagnose and evaluate hypersensitivity pneumonitis
The American College of Chest Physicians® (CHEST) recently released new clinical guidelines on the Diagnosis and Evaluation of Hypersensitivity Pneumonitis (HP).
Chill out: Advanced solar tech runs cooler and lasts longer
New mechanisms for converting sunlight to electricity more efficiently are also beneficial for extending the lifespan of solar panels
Conservationists concerned about illegal hunting and exploitation of porcupines in Indonesia
Porcupines are being illegally hunted and exploited throughout their range in Indonesia for local subsistence and commercial trade. They are reportedly in decline, yet there seems to be little control or monitoring on uptake and trade. A new study examining seizure data of porcupines in Indonesia found a total of 39 incidents from January 2013 to June 2020 involving an estimated 452 porcupines....
Controlling cholesterol in microglia alleviates chronic pain, opioid-free
Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment. Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used a mouse model to demonstrate the pivotal role of cholesterol in CIPN, and proposed a novel therapeutic approach to reverse it.
Could wider use of gene reserves protect rare species?
UK landowners and conservationists welcome wider-spread use of Gene Conservation Units (GCUs) to help protect some of the rarest plants and insects, research at the University of York has shown.
Dartmouth-led study finds overemphasis on toy giveaways in TV ads unfairly promotes fast-food to children
A new Dartmouth-led study, published this week in the journal Pediatrics, has found that the disproportionate use of premiums within child-targeted TV advertising for children's fast-food meals is deceptive, violating the industry's own self-regulatory guidelines.
Diagramming the brain with colorful connections
BARseq2 is a new brain mapping technique that can identify cells by the unique sets of genes they use. Neuroscientists can use this tool to understand how brain cells are organized and connected.
Diet, exercise and sleep linked to high risk of cardiovascular disease in autistic people
Autistic people have far greater risks of long term physical health conditions than others, but the reasons for this remain unclear. New research from the University of Cambridge suggests that unhealthy lifestyle habits may be an important contributing factor. The results are published today in the journal Molecular Autism.
Differences between leopards are greater than between brown bears and polar bears
New research demonstrates that African and Asian leopards are more genetically differentiated from one another than polar bears and brown bears. Indeed, leopards are so different that they ought to be treated as two separate species, according to a team of researchers, among them, scientists from the University of Copenhagen. This new knowledge has important implications for better conserving this...
Do purines influence cancer development?
Numerous disease development processes are linked to epigenetic modulation. One protein involved in the process of modulation and identified as an important cancer marker is BRD4. A recent study by researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, now shows that the supply of purines as well as the purine synthesis of a cell can influence BRD4...
Does driving wear you out? You might be experiencing 'accelerousal'
If you're an anxious driver, accelerousal may be in your genes. Accelerousal is a term for stress provoked by acceleration events, even small ones. New research from the University of Houston takes a look at the phenomenon.
Early screening tool leads to earlier diagnosis and treatment for autism spectrum disorder
Since it debuted in 2011, the Get SET Early program, which provides pediatricians and parents with a relatively simple process to screen for indicators of autism spectrum disorder (ASD) in children as young as age 1, has steadily grown in use and validation. Early screening and identification of ASD has been linked to more effective treatment.
Engineering diseased human skin in vitro
Professor Dong-Woo Cho's research team at POSTECH develops an artificial diabetic skin based on 3D cell printing.
Errors at the start of life
The process of combining maternal and paternal genetic information is surprisingly error-prone
Esophageal cancers resurrect ancient retroviruses hidden in our genome
Scientists have found that many esophageal cancers turn on ancient viral DNA embedded in our genome, a finding that could lead to improvements in immunotherapy.
Even small bills for health insurance may cause healthy low-income people to drop coverage
Twenty dollars a month might not seem like a lot to pay for health insurance. But for people getting by on $15,000 a year, it's enough to make some drop their coverage - especially if they're healthy, a new study of Medicaid expansion participants in Michigan finds. That could keep them from getting preventive or timely care, and could leave their insurance company with a sicker pool of patients...
Even when they include them, gifted programs aren't serving Black or low-income kids
The first nationwide study of outcomes for different gifted subgroups shows the programs may not be adequately serving their Black and low-income students.
Fat around waist more important than general obesity in predicting
New research presented at this year's European Congress on Obesity (held online, 10-13 May) shows that fat around the waist (abdominal obesity) is more important than general obesity as shown by body mass index (BMI) in predicting the severity of chest X-ray results in patients with COVID-19.
Fifty shades of reading: Who reads contemporary erotic novels and why?
New study is the first to explore empirically the readership and the reading rewards underlying the current large-scale cultural phenomenon of erotic novels
Firefighting chemical found in sea lion and fur seal pups
A chemical that the New South Wales government has recently partially banned in firefighting has been found in the pups of endangered Australian sea lions and in Australian fur seals. The finding represents another possible blow to Australian sea lions' survival. Hookworm and tuberculosis already threaten their small and diminishing population, which has fallen by more than 60 percent over four...
Flash flood risk may triple across third pole due to global warming
An international team led by researchers from the Xinjiang Institute of Ecology and Geography (XIEG) of the Chinese Academy of Sciences and the University of Geneva has found that flash floods may triple across the Earth's "Third Pole" in response to ongoing climate change.
Flower size correlates with pollinator size, evolved independently among mountains
The morphological compatibility between flowers and insects was given in the famous textbook example of Darwin's orchids and hawkmoths. As in this example, many studies have shown that geographical variations in flower size match the size of insects in each region. In other words, studies have shown "flower-sized regional adaptation" in which large flowers evolve in areas pollinated by large...
Flying at up to Mach 16 could become reality with UCF's developing propulsion system
University of Central Florida researchers are building on their technology that could pave the way for hypersonic flight, such as travel from New York to Los Angeles in under 30 minutes. In their latest research published in the journal Proceedings of the National Academy of Sciences, the researchers discovered a way to stabilize the detonation needed for hypersonic propulsion by creating a...
For twins, gesture and speech go hand-in-hand in language development
Twins produce fewer gestures and gesture to fewer objects than other children. Language use also lags for twins, and language--but not gesture--is also affected by sex, with girls performing better than boys.