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22 articles from ScienceDaily

When macrophages let off steam

New data shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged cells during inflammation play a role during this process. 'Rewiring' the mitochondria in the macrophages protects them against overloading and can thus improve the way in which parts of damaged cells are eliminated and resolve the inflammatory reaction.

Electron family creates previously unknown state of matter

An international research team has demonstrated a completely novel state of matter in a metal. It is created by the combination of four electrons-until now, only electron pairs were known. This discovery could lead to a new type of superconductivity, an entirely new research direction, and revolutionary technologies such as quantum sensors.

How cells correctly choose active genes

It is essential for cells to control precisely which of the many genes of their genetic material they use. This is done in so-called transcription factories, molecular clusters in the nucleus. Researchers have now found that the formation of transcription factories resembles the condensation of liquids. Their findings will improve the understanding of causes of diseases and advance the development...

New strategy against treatment-resistant prostate cancer identified

A new study has identified an RNA molecule that suppresses prostate tumors. The scientists found that prostate cancers develop ways to shut down this RNA molecule to allow themselves to grow. According to the new research -- conducted in mice implanted with human prostate tumor samples -- restoring this so-called long noncoding RNA could be a new strategy to treat prostate cancer that has...

Experts master defects in semiconductors

Researchers have discovered a novel way to manipulate defects in semiconductors. The study holds promising opportunities for novel forms of precision sensing, or the transfer of quantum information between physically separate qubits, as well as for improving the fundamental understanding of charge transport in semiconductors.

Pathomechanisms in heart disease discovered

The largest protein in the human body, titin, enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function and lead to heart muscle disease. The pathomechanisms behind this -- i.e. why TTN mutations trigger disease -- were unclear until now. A team of experts has now investigated these pathomechanisms in more detail and has gained...

New insights into kidney disease with tropical frog models

Using cutting-edge genetic engineering, researchers have developed a model to study hereditary kidney disease with the help of tropical frogs. The method allows them to collect large amounts of data on anomalies, which can then be analyzed using artificial intelligence. The research opens up new opportunities in the search for new treatment approaches for the hitherto incurable disease.