Researchers used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights into the ways pairs or groups of proteins fit together to carry out cellular processes could lead...

Research in mice demonstrates how diet alters a gut microbe molecule that, in turn, prompts immune cells to downregulate inflammation. The study elucidates molecular mechanism behind long-standing belief that diet, microbiota, and immunity influence one another in myriad ways. If affirmed in larger animals and humans, the findings could inform the design of small-molecule drugs that regulate...

A new study shows how dexamethasone, the main treatment for severe COVID-19 lung infections, alters how immune cells work, which may help male patients, but has little to no benefit for females.

A study of more than 200,000 U.S adults hospitalized with COVID-19 finds that, overall, patients taking immunosuppressive drugs do not face increased risk of being put on a ventilator or death.

New research offers a closer look at the relationship between decreasing demand for oil and a resilient, varied oil market -- and the carbon footprint associated with both.

Researchers have developed a high-throughput screen methodology to identify compounds affect a key G protein coupled receptor (GPCR) rhodopsin (Rh). GPCRs mediate many important physiological functions and are considered to be one of the most effective therapeutic targets for a broad spectrum of diseases, ranging from diabetes to immune system disorders.

Imagine your car starting the moment you get in because it recognizes the jacket you're wearing. Consider the value of a hospital gown that continuously measures and transmits a patient's vital signs. These are just two applications made possible by a new 'body area network'-enabling fabric.

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, researchers have found.

A new study suggests that the brain differentiates very similar environments -- such as two stores from the same supermarket chain -- as if they were even more different than two places that are nothing alike.

Using a new model of brain activity, computational neuroscientists are exploring striking bursts of activity in the human brain that have not been examined before. These bursts may have potential to serve as biomarkers for brain disease and conditions such as depression, schizophrenia, dementia, and ADHD.

Researchers have revealed a striking pattern following a functional screen of extracts from plants collected in Muir Woods National Monument, in coastal redwood forest land in California. They found plants with a long history of use by Native Americans as topical analgesics, were often also used as gastrointestinal aids.

According to physics, seismic waves from earthquakes should travel in a four-leaf clover pattern, but in the real world they behave more like ripples in a pond. New research has found the pattern hidden among low-frequency seismic waves, the kind that can topple buildings. The study looked at small earthquakes in northern Oklahoma and could change the way scientists think about potential damage...

Drinking coffee or tea may be associated with a lower risk of stroke and dementia, according to a new study. Drinking coffee was also associated with a lower risk of post-stroke dementia.

Human behavior drives the evolution of biological organisms in ways that can profoundly adversely impact human welfare. Understanding people's incentives when they do so is essential to identify policies and other strategies to improve evolutionary outcomes. In a new study, researchers bring the tools of economics and game theory to evolution management.

Researchers have used synthetic biology to bring together the best of spider silk and mussel foot protein in a biocompatible adhesive.

New research has uncovered the first fossil evidence of a rare botanical condition known as precocious germination in which seeds sprout before leaving the fruit.

Scientists have identified a new process using coordination materials that can accelerate the use of low-cost, Earth-abundant materials with the potential to transform the energy sector by replacing silicone-based solar panels.

The most common pharmaceuticals on the market are made by chaining together rings of molecules to create the drugs that treat conditions including pain, depression and leukemia. But creating those rings and forming them in a way that is tailored to each individual disease has always been a cumbersome and expensive process in medicinal chemistry. New research proposes a way to simplify that...

Immunotherapies, which harness the body's natural defenses to combat disease, have revolutionized the treatment of aggressive and deadly cancers. But often, these therapies -- especially those based on immune cells -- must be tailored to the individual patient, costing valuable time and pushing their price into the hundreds of thousands of dollars.

Turbulence makes many people uneasy or downright queasy. And it's given researchers a headache, too. Mathematicians have been trying for a century or more to understand the turbulence that arises when a flow interacts with a boundary, but a formulation has proven elusive.

Video clips are only modestly more persuasive to audiences than the written word is, according to researchers who conducted an experiment about political misinformation.

Researchers have created lightning-fast computer software that can help nations track and analyze pandemics, like the one caused by COVID-19, before they spread like wildfire around the globe.

Researchers have discovered how individual and networks of cells in an area of the brain called the retrosplenial cortex encode this angular head motion in mice to enable navigation both during the day and at night.

Climate scientists identify abrupt transitions in climate records that may have been caused by the climate system crossing a tipping point. They devised a statistical method to determine whether these transitions are simply noise or evidence of a more significant change. Their method is less error-prone than previous methods, since it doesn't rely on human determination. It also allows comparing...