151 articles from TUESDAY 17.5.2022

New protein structures to aid rational drug design

In a major advance for rational drug design, a Texas A&M AgriLife team has described several protein structures of a crucial player in cellular processes. The advance could bring new ideas for treatments of diseases such as Alzheimer's, AIDS, cancer and others.

Team develops automated platform for plasmid production

Plasmids have extensive use in basic and applied biology. These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in the production of therapeutic proteins like insulin, plasmids are broadly used in the large-scale production of many bioproducts.

Automated platform for plasmid production

Researchers have developed PlasmidMaker, a versatile automated platform for plasmid design & construction. These circular DNA molecules are used by scientists to introduce new genes into a target organism, and have extensive use in basic and applied biology. In particular, they have applications in the large-scale production of bioproducts.

Chemists skew the odds to prevent cancer

A theoretical framework shows how to increase the odds of identifying cancer-causing mutations before tumors take hold. Researchers demonstrate that only a few energetically favorable pathways are likely to lead to cancer.

New protein structures to aid rational drug design

In a major advance for rational drug design, chemists have described several protein structures of a crucial player in cellular processes. The advance could bring new ideas for treatments of diseases such as Alzheimer's, AIDS, cancer and others.

Image: Hubble reveals a river of star formation

This newly revised NASA Hubble Space Telescope image of the Hickson Compact Group 31 (HCG 31) of galaxies highlights streams of star-formation as four dwarf galaxies interact. The bright, distorted clump of young blue-white stars (top-right of center) is NGC 1741. Although it appears to be a single galaxy, NGC 1741 is actually a pair of colliding dwarf galaxies. Another dwarf, cigar-shaped galaxy...