Muscular dystrophy gene therapy nears approval, but safety concerns linger
116 articles from TUESDAY 23.5.2023
New U.S. lab will work with deadly animal pathogens—in the middle of farm country
Five years ago, when Duchenne muscular dystrophy (DMD) began making it hard for him to walk, 7-year-old Conner Curran received a blood infusion of trillions of viruses carrying a muscle gene to replace his mutant one. Within 2 months the Connecticut boy went from crawling up stairs to “flying up,” says his mother, Jessica Curran. The family and the researchers hoped he would never...
U.S. planning test reactor to run on weapons-grade uranium
Virologist Robert Cross’s lab is equipped to handle some of the world’s most dangerous viruses. At the Galveston National Laboratory he has worked with guinea pigs infected with Ebola virus and macaques carrying Lassa fever. What it can’t accommodate are pigs, which are common carriers of the deadly Nipah virus. “We’re not really geared to handle large animals,” says Cross,...
Swift, deadly epidemic kills all the black sea urchins in Gulf of Eilat, posing threat to Eilat's coral reef
The U.S. Department of Energy (DOE) is planning a small test reactor that would burn a large amount of weapons-grade uranium, according to
the project’s draft environmental assessment
. The experiment, to be built in a cost-sharing arrangement, would provide data for a new type of power reactor being developed by TerraPower and Southern Company Services. But the use of...
Using nuclear spins neighboring a lanthanide atom to create Greenberger-Horne-Zeilinger quantum states
A series of new, disturbing studies from Tel Aviv University reveals a deadly epidemic causing mass mortality of black sea urchins in the Mediterranean Sea and the Gulf of Eilat. The entire population of black sea urchins in Eilat was wiped out over a couple of months. For example, thousands of sea urchins living in a site near the northern shore of the Gulf of Eilat died out over the course of a...
Extinct offshore volcano could store gigatons of carbon dioxide
Researchers have experimentally demonstrated a new quantum information storage protocol that can be used to create Greenberger-Horne-Zeilinger (GHZ) quantum states. There is a great deal of interest in these complex entangled states because of their potential use in quantum sensing and quantum error correction applications.
Investors overvalue companies that align with presidential policies; their mistakes 'leave money on the table'
A new study published in Geology concludes that an extinct volcano off the shore of Portugal could store as much as 1.2–8.6 gigatons of carbon dioxide, the equivalent of ~24–125 years of the country's industrial emissions.
Engineers create bacteria that can synthesize an unnatural amino acid
Republican politicians typically favor low taxes and less regulation, which seems like a recipe for corporate profits and stock market success. In reality, however, this is not what happens.
Strategic city planning can help reduce urban heat island effect
In a study recently published in Nature Chemical Biology, researchers focused on para-nitro-L-phenylalanine (pN-Phe), a non-standard amino acid that is neither one of the twenty standard amino acids nor observed in nature. pN-Phe has been used by other research groups to help the immune system mount a response to proteins that it does not ordinarily respond to.
How the February 2023 Türkiye earthquakes ruptured and produced damaging shaking
The tendency of cities to trap heat—a phenomenon called the "urban heat island," often referred to as the UHI effect—can lead to dangerous temperatures in the summer months, but new Penn State research published in Buildings suggests that certain urban factors can reduce this effect.
Researchers treat depression by reversing brain signals traveling the wrong way
Three studies now published in The Seismic Record (TSR) offer an initial look at the February 6, 2023 earthquakes in south-central Türkiye and northwestern Syria, including how, where, and how fast the earthquakes ruptured and how they combined as a "devastating doublet" to produce damaging ground shaking.
- 23/5/23 21:55
How did COVID-19 lockdown impact employment of individuals with visual disabilities?
A new study has revealed how magnetic stimulation treats severe depression: by correcting the abnormal flow of brain signals.
Organizations must go beyond medical views on menopause to support women's professional aspirations, says study
New data show that while individuals with visual disabilities were slow to recover employment because of the effects of the COVID-2019 lockdown, they have made headway, depending on their level of disability, almost meeting their pre-pandemic levels. Possible reasons for their slower recovery include major safety concerns due to the shortage of personal protective equipment, less access to...
COVID-19 vaccines may undergo major overhaul this fall
Organizations must enable midlife women to thrive in the workplace by taking inspiration from societies such as China and Japan to encourage positive conversations around the impact of menopause, a new study reveals.
Evaluating the ecological impacts of mountain biking
Earlier this year, U.S. regulators settled on
a new strategy for COVID-19 vaccines
. Like the annual flu shot, the vaccines will be updated each year based on the virus’ evolution, then rolled out in the fall. Accordingly, on 15 June, advisers to the U.S. Food and Drug Administration
will weigh which strain or strains of SARS-CoV-2
should make up the next...
Newly described species of dome-headed dinosaur may have sported bristly headgear
Mountain biking is one of the most popular leisure activities today. Sport ecologists at the University of Bayreuth have now compiled and evaluated a wide range of previously published findings on the ecological consequences of this sport. Numerous direct and short-term effects on animals, plants and soils can be clearly demonstrated. However, estimates of long-term consequences remain difficult...
World's most sensitive model-independent experiment starts searching for dark matter
If you look at enough dinosaur fossils, you'll see that their skulls sport an amazing variety of bony ornaments, ranging from the horns of Triceratops and the mohawk-like crests of hadrosaurs to the bumps and knobs covering the head of Tyrannosaurus rex.
The laws of physics have not always been symmetric, which may explain why you exist
The world's most sensitive model-independent experiment to search for particularly light particles, of which dark matter might be composed, starts today at DESY in the form of the 'light shining through a wall' experiment ALPS II. Scientific calculations predict that this ominous form of matter should occur five times as often in the universe as normal, visible matter. Until now, however, no one...
Long-term study shows tree species diversity increases likelihood of planting success
For generations, physicists were sure the laws of physics were perfectly symmetric. Until they weren't.
A novel high-throughput method for screening protein-secreting microbial strains
Planting forests with diverse species can help ensure their success, according to a new study published May 18 from the Smithsonian Environmental Research Center (SERC) and The Nature Conservancy. The discovery is the result of a decade of research from BiodiversiTREE, a large-scale reforestation project at SERC designed to run for 100 years, testing the effects of different tree planting...
Multifunctional interface enables manipulation of light waves in free space
A unique method to screen large-scale libraries for industrially useful bacterial strains was recently developed by Tokyo Tech researchers. The simple approach combines biosensors and microfluidics to quickly identify mutant strains that secrete large amounts of industrially useful proteins, opening the doors to more applications, like reasonably priced biopharmaceuticals.
Precipitation variations indicate the northern boundary and climate regimes of the Asian summer monsoon
Recent technological advances have given us a remarkable ability to manipulate and control light waves, opening up numerous applications in various fields, such as optical communication, sensing, imaging, energy, and quantum computing. At the heart of this progress are photonic structures that can control light waves, either at the chip level in the form of photonic integrated circuits (PICs) or...
Precipitation patterns and their variations over the Tibetan Plateau (TP) are mainly dominated by the Asian summer monsoon (ASM), westerlies, and their interactions. The exact extent of the ASM's influence, however, remains undetermined. The northern boundary of the ASM denotes the northernmost position, with its leading edge advancing from south to north after its outbreak.