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183,606 articles from EurekAlert

3D printed models provide clearer understanding of ground motion

It seems like a smooth slab of stainless steel, but look a little closer, and you'll see a simplified cross-section of the Los Angeles sedimentary basin. Caltech researcher Sunyoung Park and her colleagues are printing 3D models like the metal Los Angeles proxy to provide a novel platform for seismic experiments.

A new method for fighting 'cold' tumors

Researchers Michael Knitz and radiation oncologist and University of Colorado Cancer Center member Sana Karam, MD, PhD, address cold tumors in new research published this week in the Journal for ImmunoTherapy of Cancer. Working with mouse models in Karam's specialty area of head and neck cancers, Knitz and Karam studied the role of T cells in tumor treatment.

A new study identifies interleukin 11 as a marker of cancer-associated fibroblasts

A research group led by Prof. Hiroyasu Nakano of Department of Biochemistry, Toho University Faculty of Medicine, found that interleukin 11 (IL-11)-positive cells rapidly appear in the colons of mice with colitis and colitis-associated colorectal cancers. In RNA-seq analysis of the gene expression profiles, they found that high expression of enriched genes in IL-11-positive fibroblasts correlated...

ALMA discovers rotating infant galaxy with help of natural cosmic telescope

Using ALMA, astronomers found a rotating baby galaxy 1/100th the size of the Milky Way at a time when the Universe was only seven percent of its present age. Thanks to assistance by the gravitational lens effect, the team was able to explore for the first time the nature of small and dark "normal galaxies" in the early Universe, which greatly advances our understanding of the initial phase of...

Among COVID-19 survivors, an increased risk of death, serious illness

Researchers at Washington University School of Medicine in St. Louis showed that COVID-19 survivors -- including those not sick enough to be hospitalized -- have an increased risk of death in the six months following diagnosis with the virus. They also have catalogued the numerous diseases associated with COVID-19, providing a big-picture overview of the long-term complications of COVID-19 and...

Anti-aging compound improves muscle glucose metabolism in people

In the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.

Artificial intelligence model predicts which key of the immune system opens the locks of coronavirus

With an artificial intelligence (AI) method developed by researchers at Aalto University and University of Helsinki, researchers can now link immune cells to their targets and for example uncouple which white blood cells recognize SARS-CoV-2. The developed tool has broad applications in understanding the function of immune system in infections, autoimmune disorders, and cancer.

Better country dementia care

Rising levels of dementia is putting pressure on residential aged care facilities, including in rural and regional centres where nursing homes and staff are already under pressure. Now a pilot program of personalised interventions, including residents' favourite songs, has been shown to make a big difference to dementia behaviours, drug use and carers' wellbeing.

Burns victims struggling to pay

Living away from community and country, Aboriginal families of children with severe burns also face critical financial stress to cover the associated costs of health care and treatment, a new study shows. An Australian study found feelings of crisis were common in Aboriginal families with children suffering severe burns, with one family reporting skipping meals and others selling assets to reduce...

Common antibiotic effective in healing coral disease lesions

An antibiotic used to treat bacterial infections in humans is showing promise in treating stony coral, found throughout the tropical western Atlantic, including several areas currently affected by stony coral tissue loss disease. Preserving M. cavernosa colonies is important due to its high abundance and role as a dominant reef builder in the northern section of Florida's Coral Reef. Results show...

COVID-19 vaccine development built on >$17 billion in NIH funding for vaccine technologies

The unprecedented development of COVID-19 vaccines less than a year after discovery of this virus was enabled by more than $17 billion of research on vaccine technologies funded by the NIH prior to the pandemic, according to new research from Bentley University's Center for Integration of Science and Industry. The article, "NIH funding for vaccine readiness before the COVID-19 pandemic,"...

During pandemic's first 9 months, depression and anxiety increased sharply among Americans

Boston College researchers found that 50 percent of adults reported anxiety and 44 percent reported depression between April and November 2020 - rates six times higher than 2019 - according to a new report in the journal Translational Behavioral Medicine. Rates of anxiety and depression were nearly twice as high for young adults than for older adults, and were also elevated among Blacks and...

Emergency EMR created in a week to respond to COVID-19 crisis

A paper published in the International Journal of Medical Informatics shows how a team from Regenstrief Institute leveraged OpenMRS, a global open-source EMR, to create -- in a week -- an emergency EMR for first responders preparing for a possible influx of COVID-19 patients. Lessons learned can be applied to future health crises.

Experimental drug shows potential against Alzheimer's disease

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. The study was published online today in the journal Cell.

Fighting harmful bacteria with nanoparticles

Multi-resistant pathogens are a serious and increasing problem in today's medicine. Where antibiotics are ineffective, these bacteria can cause life-threatening infections. Researchers at Empa and ETH Zurich are currently developing nanoparticles that can be used to detect and kill multi-resistant pathogens that hide inside our body cells. The team published the study in the current issue of the...

How is a molecular machine assembled?

The conversion of light into chemical energy by plants and photosynthetic microorganisms is one of the most important processes in nature, removing climate-damaging CO2 from the atmosphere. Protein complexes, so-called photosystems, play the key role in this process. An international research team shed light for the first time on the structure and function of a transition state in the synthesis of...

Hunger cues

Research by investigators at Harvard Medical School illuminates the neurobiology that underlies food attraction and how hungry mice choose to pay attention to one object in their environment over another.

Immune system, not COVID virus, may pose greatest risk to pregnant women

A team of Yale scientists decided to investigate whether the virus could be affecting placental tissue of infected expectant mothers. Their analysis found that while evidence of the virus in the placenta is rare, the placenta in infected mothers tended to exhibit a much higher level of immune system activity than those of non-infected pregnant women, they report April 22 in the journal Med.

Improving survival in pancreatic cancer

Nagoya University researchers and colleagues have uncovered a molecular pathway that enhances chemotherapy resistance in some pancreatic cancer patients. Targeting an RNA to interrupt its activity could improve patient response to therapy and increase their overall survival.

Individuals in lower-income US counties or high support for former President Trump continue to be less likely to socially distance

Using nearly a year of anonymous geolocation data from 15-17 million cell phone users in 3,037 United States counties, investigators have found that individuals with lower income per capita or greater Republican orientation were associated with significantly reduced social distancing throughout the study period from March 2020 through January 2021. Their findings are reported in the American...

International research teams explore genetic effects of Chernobyl radiation

Researchers utilized genomic tools to investigate potential health effects of exposure to ionizing radiation, a known carcinogen, as a result of the 1986 Chernobyl accident. One study found no evidence that genetic changes associated with radiation exposure are passed to children, while the second study documented the genetic changes in the tumors of people who developed thyroid cancer after being...