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183,606 articles from EurekAlert
'Stickiness' key to better diagnostics and pharmaceuticals
The 'stickiness', or viscosity, of microscopic liquids can now be measured thousands of times faster than ever before, potentially leading to better understanding of living cells, disease diagnostics and pharmaceutical testing.
3D printed models provide clearer understanding of ground motion
It seems like a smooth slab of stainless steel, but look a little closer, and you'll see a simplified cross-section of the Los Angeles sedimentary basin. Caltech researcher Sunyoung Park and her colleagues are printing 3D models like the metal Los Angeles proxy to provide a novel platform for seismic experiments.
A new method for fighting 'cold' tumors
Researchers Michael Knitz and radiation oncologist and University of Colorado Cancer Center member Sana Karam, MD, PhD, address cold tumors in new research published this week in the Journal for ImmunoTherapy of Cancer. Working with mouse models in Karam's specialty area of head and neck cancers, Knitz and Karam studied the role of T cells in tumor treatment.
A new study identifies interleukin 11 as a marker of cancer-associated fibroblasts
A research group led by Prof. Hiroyasu Nakano of Department of Biochemistry, Toho University Faculty of Medicine, found that interleukin 11 (IL-11)-positive cells rapidly appear in the colons of mice with colitis and colitis-associated colorectal cancers. In RNA-seq analysis of the gene expression profiles, they found that high expression of enriched genes in IL-11-positive fibroblasts correlated...
Acute ischemic stroke during convalescent phase of asymptomatic COVID-2019 infection in men
What The Study Did: This case series reports the risk factors, incidence rate and features of acute ischemic stroke experienced by a group of male patients ages 50 years or younger in the convalescent stage of COVID-19.
Adversity in early life linked to higher risk of mental health problems
New research has found that childhood adversity, such as parental conflict, death of a close family member or serious injury, before the age of nine was associated with mental health problems in late adolescence.
ALMA discovers rotating infant galaxy with help of natural cosmic telescope
Using ALMA, astronomers found a rotating baby galaxy 1/100th the size of the Milky Way at a time when the Universe was only seven percent of its present age. Thanks to assistance by the gravitational lens effect, the team was able to explore for the first time the nature of small and dark "normal galaxies" in the early Universe, which greatly advances our understanding of the initial phase of...
Among COVID-19 survivors, an increased risk of death, serious illness
Researchers at Washington University School of Medicine in St. Louis showed that COVID-19 survivors -- including those not sick enough to be hospitalized -- have an increased risk of death in the six months following diagnosis with the virus. They also have catalogued the numerous diseases associated with COVID-19, providing a big-picture overview of the long-term complications of COVID-19 and...
Ancient Indigenous forest gardens promote a healthy ecosystem: SFU study
A new study by Simon Fraser University historical ecologists finds that Indigenous-managed forests--cared for as "forest gardens"--contain more biologically and functionally diverse species than surrounding conifer-dominated forests and create important habitat for animals and pollinators.
Anti-aging compound improves muscle glucose metabolism in people
In the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.
Artificial intelligence could create better outcomes for bowel cancer patients
A test which uses artificial intelligence (AI) to measure proteins present in some patients with advanced bowel cancer could hold the key to more targeted treatment, according to research published today.
Artificial intelligence model predicts which key of the immune system opens the locks of coronavirus
With an artificial intelligence (AI) method developed by researchers at Aalto University and University of Helsinki, researchers can now link immune cells to their targets and for example uncouple which white blood cells recognize SARS-CoV-2. The developed tool has broad applications in understanding the function of immune system in infections, autoimmune disorders, and cancer.
Average-risk individuals may prefer stool-based test over colonoscopy for cancer screening
When given a choice, most individuals with an average risk of colorectal cancer said they would prefer a stool-based screening test for colorectal cancer over colonoscopy, the method most often recommended by health care providers.
Better country dementia care
Rising levels of dementia is putting pressure on residential aged care facilities, including in rural and regional centres where nursing homes and staff are already under pressure. Now a pilot program of personalised interventions, including residents' favourite songs, has been shown to make a big difference to dementia behaviours, drug use and carers' wellbeing.
Blacks, hispanics, impoverished have worse survival rates among teens, adults under 40 with cancer
DALLAS - April 22, 2021 - Being Black or Hispanic, living in high-poverty neighborhoods, and having Medicaid or no insurance coverage are associated with higher mortality in men and women under 40 with cancer, a review by UT Southwestern Medical Center researchers found.
Burns victims struggling to pay
Living away from community and country, Aboriginal families of children with severe burns also face critical financial stress to cover the associated costs of health care and treatment, a new study shows. An Australian study found feelings of crisis were common in Aboriginal families with children suffering severe burns, with one family reporting skipping meals and others selling assets to reduce...
California's wildfire season has lengthened, and its peak is now earlier in the year
Researchers at the University of California, Irvine have analyzed CALFIRE wildfire statistics from 2000 to 2019, comparing them with data from 1920 to 1999, to learn that the annual burn season has lengthened in the past two decades and that the yearly peak has shifted from August to July. A new study on the subject was published today in Nature Scientific Reports.
Can machine learning improve debris flow warning?
Machine learning could provide up an extra hour of warning time for debris flows along the Illgraben torrent in Switzerland, researchers report at the Seismological Society of America (SSA)'s 2021 Annual Meeting
Cannabis use disorder rate rose among pregnant women between 2001-2012
Babies born to mothers diagnosed with cannabis use disorder are more likely to experience negative health outcomes, such as preterm birth and low birth weight, than babies born to mothers without a cannabis use disorder diagnosis, report UC San Diego researchers.
Climate-smart ag strategies may cut nitrous oxide emissions from corn production
For corn, using dairy manure and legume cover crops in crop rotations can reduce the need for inorganic nitrogen fertilizer and protect water quality, but these practices also can contribute to emissions of nitrous oxide -- a potent greenhouse gas.
Common antibiotic effective in healing coral disease lesions
An antibiotic used to treat bacterial infections in humans is showing promise in treating stony coral, found throughout the tropical western Atlantic, including several areas currently affected by stony coral tissue loss disease. Preserving M. cavernosa colonies is important due to its high abundance and role as a dominant reef builder in the northern section of Florida's Coral Reef. Results show...
COVID-19 vaccine development built on >$17 billion in NIH funding for vaccine technologies
The unprecedented development of COVID-19 vaccines less than a year after discovery of this virus was enabled by more than $17 billion of research on vaccine technologies funded by the NIH prior to the pandemic, according to new research from Bentley University's Center for Integration of Science and Industry. The article, "NIH funding for vaccine readiness before the COVID-19 pandemic,"...
During pandemic's first 9 months, depression and anxiety increased sharply among Americans
Boston College researchers found that 50 percent of adults reported anxiety and 44 percent reported depression between April and November 2020 - rates six times higher than 2019 - according to a new report in the journal Translational Behavioral Medicine. Rates of anxiety and depression were nearly twice as high for young adults than for older adults, and were also elevated among Blacks and...
Emergency EMR created in a week to respond to COVID-19 crisis
A paper published in the International Journal of Medical Informatics shows how a team from Regenstrief Institute leveraged OpenMRS, a global open-source EMR, to create -- in a week -- an emergency EMR for first responders preparing for a possible influx of COVID-19 patients. Lessons learned can be applied to future health crises.
Experimental drug shows potential against Alzheimer's disease
Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. The study was published online today in the journal Cell.
Faster air exchange in buildings not always beneficial for coronavirus levels
Vigorous and rapid air exchanges might not always be a good thing when it comes to levels of coronavirus particles in a multiroom building, according to a new modeling study. Particle levels can spike in downstream rooms shortly after rapid ventilation.
Fat-footed tyrannosaur parents could not keep up with their skinnier adolescent offspring
New research by the University of New England's Palaeoscience Research Centre suggests juvenile tyrannosaurs were slenderer and relatively faster for their body size compared to their multi-tonne parents.
Fighting harmful bacteria with nanoparticles
Multi-resistant pathogens are a serious and increasing problem in today's medicine. Where antibiotics are ineffective, these bacteria can cause life-threatening infections. Researchers at Empa and ETH Zurich are currently developing nanoparticles that can be used to detect and kill multi-resistant pathogens that hide inside our body cells. The team published the study in the current issue of the...
Firearms laws curb rates of gun violence across United States
States with stricter firearms laws reported lower suicide and homicide rates, according to a Rutgers study.
Freeze! Executioner protein caught in the act
A new molecular 'freeze frame' technique has allowed WEHI researchers to see key steps in how the protein MLKL kills cells.
Frequent internet use by older people during lockdown linked to mental health benefits
A new study from the University of Surrey has found that among people aged 55 to 75 more frequent use of the internet was beneficial for mental health and quality of life under lockdown.
Ground and satellite observations map building damage after Beirut explosion
Days after the 4 August 2020 massive explosion at the port of Beirut in Lebanon, researchers were on the ground mapping the impacts of the explosion in the port and surrounding city. The goal was to document and preserve data on structural and façade damage before rebuilding.
How is a molecular machine assembled?
The conversion of light into chemical energy by plants and photosynthetic microorganisms is one of the most important processes in nature, removing climate-damaging CO2 from the atmosphere. Protein complexes, so-called photosystems, play the key role in this process. An international research team shed light for the first time on the structure and function of a transition state in the synthesis of...
How we know whether and when to pay attention
International team of researchers identifies cognitive computations underlying human predictive behaviour.
Hunger cues
Research by investigators at Harvard Medical School illuminates the neurobiology that underlies food attraction and how hungry mice choose to pay attention to one object in their environment over another.
Hungry fruit flies are extreme ultramarathon fliers
New research indicates that the common fruit fly can travel tens of kilometers in a single flight when in search of food.
Immune system, not COVID virus, may pose greatest risk to pregnant women
A team of Yale scientists decided to investigate whether the virus could be affecting placental tissue of infected expectant mothers. Their analysis found that while evidence of the virus in the placenta is rare, the placenta in infected mothers tended to exhibit a much higher level of immune system activity than those of non-infected pregnant women, they report April 22 in the journal Med.
Improving survival in pancreatic cancer
Nagoya University researchers and colleagues have uncovered a molecular pathway that enhances chemotherapy resistance in some pancreatic cancer patients. Targeting an RNA to interrupt its activity could improve patient response to therapy and increase their overall survival.
Increased tourniquet use has saved lives in Los Angeles County
Tourniquet use has been consistently increasing in Los Angeles County since 2015 and is significantly associated with improved patient survival.
Individuals in lower-income US counties or high support for former President Trump continue to be less likely to socially distance
Using nearly a year of anonymous geolocation data from 15-17 million cell phone users in 3,037 United States counties, investigators have found that individuals with lower income per capita or greater Republican orientation were associated with significantly reduced social distancing throughout the study period from March 2020 through January 2021. Their findings are reported in the American...
Inspired by nature, the research to develop a new load-bearing material
Engineers have developed a new material that mimics human cartilage - the body's shock absorbing and lubrication system, and it could herald the development of a new generation of lightweight bearings.
International research teams explore genetic effects of Chernobyl radiation
Researchers utilized genomic tools to investigate potential health effects of exposure to ionizing radiation, a known carcinogen, as a result of the 1986 Chernobyl accident. One study found no evidence that genetic changes associated with radiation exposure are passed to children, while the second study documented the genetic changes in the tumors of people who developed thyroid cancer after being...
IU researchers tackled the challenges of conducting intrastate policy surveillance
IU researchers tackled the challenges of conducting intrastate policy surveillance by looking at accessibility of county and municipal laws in Indiana.
Know your ally: Cooperative male dolphins can tell who's on their team
When it comes to friendships and rivalries, male dolphins know who the good team players are. New findings, published in Nature Communications by University of Bristol researchers, reveal that male dolphins form a social concept of team membership based on cooperative investment in the team.
Landscape induced back-building thunderstorm lines along the mei-yu front
A research team led by Dr. Zhemin Tan, Professor at the School of Atmospheric Sciences of Nanjing University, analyzed the influences of the regional landscape that lead to consistent mesoscale convective systems (MCS) back-building in the Yangtze river basin.
Less is more for the next generation of CAR T cells
Penn Medicine researchers discovered that less is more when it comes to the length of what is known as the single-chain variable fragment for CAR T cells.
Machine learning model generates realistic seismic waveforms
A new machine-learning model that generates realistic seismic waveforms will reduce manual labor and improve earthquake detection, according to a study published recently in JGR Solid Earth.
Mars has right ingredients for present-day microbial life beneath its surface, study finds
New research suggests that rocks in the Martian crust could produce the same kind of chemical energy that supports microbial life deep beneath Earth's surface.
Mars' changing habitability recorded by ancient dune fields in Gale crater
An international team led by Imperial has found evidence of ancient dunes on Mars that could help explain ancient surface conditions.
Maternal, neonatal outcomes among pregnant women with, without COVID-19
What The Study Did:Â This study assesses the association between COVID-19 and maternal and neonatal outcomes in pregnant women with COVID-19 diagnosis compared with pregnant women without COVID-19 diagnosis.