Early antiviral response in the nose may determine the course of COVID-19
191,281 articles from EurekAlert
Experiences, perpetration of identity-based bullying among adolescents
How early is the course of COVID-19, mild or severe, determined? In Cell, researchers examined nasal cells sampled from patients at the time of diagnosis, looking for differences between those who developed severe disease and those who experienced a mild illness. Cells from patients who developed severe COVID-19 exhibited a more muted antiviral response. If the early stages of infection can...
Featured articles from the journal CHEST®, July 2021
What The Study Did: Using survey responses from students in some Pittsburgh, Pennsylvania, high schools, researchers investigated how experiences of bullying based on race/ethnicity/national origin and other marginalized identities are associated with outcomes for health, mental health and violence among adolescents.
Four themes identified as contributors to diseases of despair in Pennsylvania
The July issue of the journal CHESTÂ® includes 85 articles, including "Pulmonary Function and Radiologic Features in Survivors of Critical COVID-19: A 3-Month Prospective Cohort," original research on critical COVID cases.
High school student presents on oral-health impact profile 5: analyzing a private practice adult population's distribution
Financial instability, lack of infrastructure, a deteriorating sense of community and family fragmentation are key contributors to diseases of despair in Pennsylvania communities, according to Penn State College of Medicine and Highmark Health researchers. The researchers conducted four focus groups in Pennsylvania communities identified as having high rates of despair-related illnesses.
How the brain paints the beauty of a landscape
Hiba Nasir, Wayzata High School, Plymouth, Minn., presented the poster "Oral-Health Impact Profile 5: Analyzing A Private Practice Adult Population's Distribution" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual...
Meeting global climate targets will lead to 8 million more energy jobs worldwide by 2050
Researchers investigate how our brains proceed from merely seeing a landscape to feeling its aesthetic impact
Mount Sinai researchers develop novel therapy that could be effective in many cancers
Researchers created a global dataset of job footprints in 50 countries and used a model to investigate how trying to meet the Paris Agreement global climate target of staying well below 2Â°C would affect energy sector jobs. They found that action to reach said target would increase net jobs by about 8 million by 2050, primarily due to gains in the solar and wind industries. The analysis appears...
Neuroscientists posit that brain region is a key locus of learning
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.
New 'atlas' charts how antibodies attack spike protein variants
Long thought of as a generic alarm system, the locus coeruleus may actually be a sophisticated regulator of learning and behavior, according to a new review by MIT researchers. They will test this hypothesis with a new grant.
New insights into immune responses to malaria
Now, researchers from Brigham and Women's Hospital and collaborators have created an "atlas" that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinary, the spike protein, as it has evolved since 2020. Their study, published in Cell, highlights antibodies that are able to neutralize the newer strains, while identifying regions of the spike protein that have become...
New measure of tropical forest vulnerability to help avoid 'tipping point'
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
New organ-on-a-chip finds crucial interaction between blood, ovarian cancer tumors
Humid tropical forests, vital in global efforts to limit rising temperatures, are under threat as a result of changes in land use and climate. Now, researchers reporting in the journal One Earth on July 23 have developed a new way to keep tabs on the vulnerability of these forests on a global scale using satellite data called the tropical forest vulnerability index (TFVI).
New tracking system monitors danger to rainforests
Researchers at Texas A&M University are pushing organ-on-a-chip devices to new levels that could change the way clinicians approach cancer treatment, particularly ovarian cancer. A team has recently submitted a patent disclosure with the Texas A&M Engineering Experiment Station.
New understanding of cell stability with potential to improve immune cell therapies
Similar to the election needle and the stock market index, scientists have developed a new tracking system to detect danger to rainforests around the world. The data to build the index was culled from advanced satellite measurements of climate and vegetation of each tropical region on Earth.
Novel imaging agent identifies biomarker for iron-targeted cancer therapies
Research in mice, published today in Science Immunology by researchers at the Babraham Institute, UK and VIB-KU Leuven, Belgium, provides two solutions with potential to overcome a key clinical limitation of immune cell therapies.
Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients. The radiotracer, 18F-TRX, can be used to measure iron concentration in tumors, which can help predict whether a not the cancer will respond to treatment. This research was published in the July issue of The Journal of Nuclear Medicine.
Phase two CD19-antibody-drug conjugate trial demonstrates promise for aggressive lymphoma
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are activated by RA-induced Fgr expression
Policing the digital divide: How racial bias can limit Internet access for people of color
MUSC Hollings Cancer Center was one of 28 clinical sites around the world that participated in the LOTIS-2 trial to test the efficacy of Loncastuximab tesirine, a promising new treatment for aggressive B-cell lymphoma. The results of the single-arm, phase 2 trial were published online in May 2021 in Lancet Oncology.
Research 'final nail in the coffin' of Paranthropus as hard object feeders
A new study from the Annenberg School for Communication at the University of Pennsylvania investigated the ways that institutions control who has access to Wi-Fi. The findings indicate that powerful institutions and privileged people use quality-of-life policing -- the report and/or arrest of individuals engaged in nonviolent offenses such as loitering, noise violations, and public intoxication --...
Research identifies potential role of 'junk DNA' sequence in aging, cancer
New research from the University of Otago debunks a long-held belief about our ancestors' eating habits.
Researchers uncover fatal flaw in green pigmented concrete
Researchers at Washington State University have recently identified a DNA region known as VNTR2-1 that appears to drive the activity of the telomerase gene, which has been shown to prevent aging in certain types of cells. Knowing how the telomerase gene is regulated and activated and why it is only active in certain cell types could someday be the key to understanding how humans age and how to...
Reverse optogenetic tool developed
Researchers from Xi'an Jiaotong-Liverpool University have found that an impurity present in many industrial pigmentations drastically reduces the strength and longevity of green architectural concrete.
Scientists identify five new plant species in Bolivia
A new optogenetic tool, a protein that can be controlled by light, has been characterized by researchers at Ruhr-UniversitÃ¤t Bochum. They used an opsin - a protein that occurs in the brain and eyes - from zebrafish and introduced it into the brain of mice. Unlike other optogenetic tools, this opsin is not switched on but rather switched off by light. Experiments also showed that the tool could...
Shedding light on the dark side of firm lobbying
Scientists have identified five new plant species in the Bolivian Andes. The species are all part of the genus Jacquemontia, which are twining or trailing plants with pretty blue flowers.
A firm's focus on customers may be diminished when it lobbies. Firm focus can be reoriented to customers, but doing so requires intentional, marketing-focused efforts.