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168,100 articles from ScienceDaily

Screening effort turns up multiple potential anti-malaria compounds; Possible resistance-proof drug pairs found

Numerous potential anti-malarial candidate drugs have been uncovered by researchers. Researchers used robotic, ultra-high-throughput screening technology to test more than 2,800 chemical compounds for activity against 61 genetically diverse strains of lab-grown malaria parasites. They found 32 compounds that were highly effective at killing at least 45 of the 61...

Breakthrough in photonic chip research paves way for ultrafast information sharing

Researchers have discovered a way to prevent light signals on a silicon chip from reflecting backwards and interfering with its operation. Otherwise, the light beams would interfere with lasers and other photonic components on the chip and make the chip unstable. The breakthrough marks a significant achievement in the development of integrated photonic chips that could replace electronic chips as...

Briny water may be at work in seasonal flows on Mars

Dark, narrow features running down slopes in the warmer regions of Mars point to the possibility of salty water as the causing agent. Never observed before and strongly associated with the warmer seasons on Mars, the features show growth, suggesting they may form near the surface today in rare times and places.Never observed before and strongly associated with the warmer seasons on Mars, the...

Poorly controlled asthma costly, study finds

Poorly controlled asthma more than doubles health-care costs associated with the disease and threatens educational achievement through a dramatic increase in school absence, according to researchers. It highlights the toll that poorly controlled asthma takes on children. It also points to an...

Hormone reduces risk of heart failure from chemotherapy, study suggests

A new study utilizing a heart failure model is providing insight into one way to coax the cardiac stem cells into repairing the damaged heart. The research finds that low doses of erythropoietin (EPO), a hormone best known for controlling the production of red blood cells, might reduce the risk of heart failure associated with some anticancer...

Human skin cells converted directly into functional neurons

Researchers have directly converted human skin cells into functional forebrain neurons, without the need for stem cells of any kind. The findings offer a new and potentially more direct way to produce replacement cell therapies for Alzheimer's and other neurodegenerative diseases. Such cells may prove especially useful for testing new therapeutic...

Molecular mechanisms offer hope for new pain treatments

By working with individuals suffering from a severe disorder that causes sensory neurons to degenerate, researchers have discovered how a specific genetic mutation causes their patients' condition, which in turn has revealed more information about the mechanisms in our bodies which enable us to sense...

Mutation linked with the absence of fingerprints

Scientists have identified a mutation that might underlie an extremely rare condition, called "adermatoglyphia," which causes people to be born without any fingerprints. The research not only provides valuable insight into the genetic basis of adermatoglyphia and of typical fingerprint formation but also underscores the usefulness of rare genetic mutations as a tool for investigating unknown...

Bypassing stem cells, scientists make neurons directly from human skin

Researchers have come up with a recipe for making functional neurons directly from human skin cells, including those taken from patients with Alzheimer's disease. The new method may offer a critical short cut for generating neurons for replacement therapies of the future. Already, the converted neurons are beginning to yield insights into what goes wrong in the Alzheimer's brain and how diseased...