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168,137 articles from ScienceDaily

New Clue Emerges For Cellular Damage In Huntington's Disease

Huntington's disease is caused by a single mutated gene that creates proteins with abnormally long repeats of the amino acid glutamine. These proteins misfold and clump together, damaging and eventually killing neurons. Yet the steps that trigger cell death have not been clarified. This study reports one early trigger: The misfolded proteins interfere with the cell's ability to move proteins...

Two Cancer Drugs Prevent, Reverse Type 1 Diabetes, Animal Study Shows

Two common cancer drugs have been shown to both prevent and reverse type 1 diabetes in a mouse model of the disease, according to new research. The drugs -- imatinib (marketed as Gleevec) and sunitinib (marketed as Sutent) -- were found to put type 1 diabetes into remission in 80 percent of the test mice and work permanently in 80 percent of those that go into...

Nations Around World Mark 10th Anniversary Of International Space Station

Nations around the world will join together to mark a milestone in space exploration this week, celebrating the 10th birthday of a unique research laboratory, the International Space Station. Now the largest spacecraft ever built, the orbital assembly of the space station began with the launch from Kazakhstan of its first bus-sized component, Zarya, on Nov. 20, 1998. The launch began an...

Biomedical Engineers' Detective Work Reveals Antibiotic Mechanism

Biomedical researchers used a series of genetic clues to uncover how certain antibiotics kill bacteria. They focused on finding the precise trigger that caused over-production of hydroxyl radical molecules and how misfolded proteins get delivered to the cell membrane, which with other steps contributes to cell...

A New Way To Remove Unwanted Heparin From Blood

Scientists in Poland are reporting development of a potential new way to quickly remove the anticoagulant heparin from patients' blood in order to avoid unwanted side effects that can happen with the current use of that blood thinner.

Water Vapor Confirmed As Major Player In Climate Change

Water vapor is known to be Earth's most abundant greenhouse gas, but the extent of its contribution to global warming has been debated. Using recent NASA satellite data, researchers have estimated more precisely than ever the heat-trapping effect of water in the air, validating the role of the gas as a critical component of climate...

'Orphan' Genes Play An Important Role In Evolution

Every group of animals possesses a small proportion of genes which are extremely variable among closely related species or even unique. Such genes are referred to as "novel," "orphan" or "taxonomically restricted." Their function and origin are often obscure. What are these genes needed for? A new paper, published in this week's issue of the online open access journal, PLoS Biology, explores this...

Immune System And Intestinal Bacteria: The Key To Balanced Cohabitation

Researchers have just discovered a key mechanism that maintains the essential balance between bacteria living in our intestine and the immune system controlling them. Their research, published in the journal Nature, paves the way for new forms of treatment for infectious diseases of the intestine, such as dysentery, or chronic inflammatory diseases, such as Crohn's...

Arsenic Linked To Cardiovascular Disease At EPA-regulated Drinking Water Standards

When mice are exposed to arsenic at federally-approved levels for drinking water, pores in liver blood vessels close, potentially leading to cardiovascular disease, say researchers. The study, while preliminary, also reveals how an enzyme linked to hypertension and atherosclerosis alters cells, and may call into question current US Environmental Protection Agency standards that are based solely on...

Helping Children And Teens Deal With Stress In An Uncertain Time

A psychologist whose research focuses on the relationship between psychological thriving and coping processes during major life transitions says that in these uncertain times, children of any age, including teens, need to be reassured that they are safe and will be cared for no matter how the family is...