Lansoprazole is a proton pump inhibitor which powerfully suppresses gastric acid production and is widely prescribed for chronic use in gastroesophageal reflux disease. Lansoprazole uncommonly causes chronic watery diarrhea unresponsive to conventional medication as a symptom of collagenous colitis. This association has recently been reported and is not widely known. Correct diagnosis and...

Some Michigan mammal species are rapidly expanding their ranges northward, apparently in response to climate change, a new study shows. In the process, these historically southern species are replacing their northern counterparts.

The time-honored tradition of displaying emotions to try to get a better deal might actually work, but inflating emotions can backfire, according to a new study in the Journal of Consumer Research.

A home-based diet and exercise program reduced the rate of functional decline among older, overweight long-term survivors of colorectal, breast and prostate cancer, according to a study in the May 13 issue of JAMA.

DNA analysis shows that Indonesian zebu cattle have a unique origin with banteng (Bos javanicus) as part of their ancestry.

Early diagnosis and treatment of Alzheimer's disease could save millions or even billions of dollars while simultaneously improving care, according to new work by University of Wisconsin-Madison researchers.

Elderly Medicare beneficiaries are more satisfied with their health care, and experience fewer problems accessing and paying for care, than Americans with employer-sponsored insurance, according to a study by Commonwealth Fund researchers published today on the Health Affairs Web site.

Improving the environment in which rats are reared can significantly strengthen the physiological process of wound healing.

Improving the environment in which rats are reared can significantly strengthen the physiological process of wound healing, according to a report in the open-access journal PLoS ONE. Researchers from the Benson-Henry Institute for Mind Body Medicine at Massachusetts General Hospital and Shriners Burns Hospital found that giving rats living in isolation the opportunity to build nests led to better...

Farnesoid X receptor is a member of the ligand-activated nuclear hormone receptor superfamily. It functions as heterodimer with retinoid X receptor and binds genomic DNA of the target genes promoters containing an inverted repeat sequence in which consensus receptor-binding hexamers are separated by one nucleotide. Cystathionase catalyzes essential steps in the trans-sulfuration pathway that leads...

When consumers find themselves in stores with narrow aisles, they react in a surprising way: they seek variety. According to a new study in the Journal of Consumer Research, confined spaces might help people diversify their choices.

Kids always seem to be ahead of trends, and marketers realize the importance of new products and services taking off with the younger set. A new study in the Journal of Consumer Research helps identify which children might be the trendsetters of their generation.

Do biofuels always create smaller carbon footprints than their fossil-fuel competitors? Not necessarily, finds a paper published today in Elsevier's Environmental Impact Assessment Review.

A home-based program aimed at improving exercise and diet can lead to meaningful improvements in physical function among older long-term cancer survivors, according to the results of a study led by researchers from Duke University Medical Center and the University of Texas M. D. Anderson Cancer Center.

UCLA researchers report that certain regions of the brain in long-term meditators were larger than non-meditators. Specifically, meditators showed significantly larger volumes of the hippocampus, and within the orbito-frontal cortex, thalamus and inferior temporal gyrus, all regions of the brain known for regulating emotions.

High serum ferritin, being a hallmark of hereditary hemochromatosis , is frequently found in chronic hepatitis C, alcoholic or non-alcoholic steatohepatitis and non-alcoholic fatty liver disease patients . A study in Italy has investigated the link between ferritin and steatosis in a non-obese cohort of non-alcoholic patients. In southern European populations, high ferritin levels, after exclusion...

Although low socioeconomic status is associated with an increased liability to smoke, performing well at school can mitigate this effect. A new study, published in BioMed Central's open-access International Journal for Equity in Health, has shown that high-achieving schoolchildren, even those from poor backgrounds, are less likely to smoke.

If two people have the same genetic disease, why would one person go blind in childhood but the other later in life or not at all? For a group of genetic diseases -- so-called ciliary diseases that include Bardet-Biedl syndrome, Meckel-Gruber syndrome and Joubert syndrome -- the answer lies in one gene that is already linked to two of these diseases and also seems to increase the risk of...

The Society of Interventional Radiology hailed the extension of an American College of Radiology resolution in support of clinical patient management by vascular and interventional radiologists as an important reminder of the critical contribution these minimally invasive specialists bring to quality patient health care.

In addition to the study highlighted in the press release, this JNCI issue includes a review of traditional and updated phase I trial designs; a study and editorial examining lymphovascular invasion and high risk breast cancer; data showing how four immunohistochemistry tests can distinguish between luminal A and B cancer subtypes; an extended follow-up examining occupational formaldehyde exposure...

Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, according to a study in the May 13 issue of JAMA.

MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins. High levels of miR-196a, a microRNA suppressing the expression of specific homebox genes that are of high relevance for the development of human embryo, activated oncogenic pathways inside human tumor cells and induced tumor cell dissemination....

Scientists have long known that members of the phenoloxidase family are involved in skin and hair coloring. When they are mutated, they can cause albinism. Produced over abundantly, they are associated with melanoma. A team of Baylor College of Medicine and German researchers explain how hemocyanin is activated -- a finding that could lead to a better understanding of both ends of the skin and...

Although most Americans take the safety of their drinking water for granted, that ordinary tap water could become deadly within minutes, says Prof. Abraham Katzir of Tel Aviv University's School of Physics and Astronomy.