New 3-D cultured cells mimic the progress of NASH

A research team led by scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, has successfully established 3-D cultured tissue that mimics liver fibrosis, a key characteristic of non-alcoholic steatohepatitis (NASH). For making the 3-D culture, cells were collected from liver tissues of NASH model mice. Their findings open up an alternative avenue for developing drugs for NASH patients, identifying new markers for early diagnosis, and better understanding the disease progression. Their findings were published in Biomaterials on Jan 27th, 2020.