New genetic signatures in childhood leukemia create paths for precision medicine

Researchers with Nemours Children's Health System utilized Next Generation Sequencing (NGS) to more precisely identify genomic characteristics of leukemias in children, the most common childhood cancer. The study, published today in BMC Medical Genomics, identified new genetic structural variants that could be used to assess the presence of minimal residual disease during the course of chemotherapy and help determine response to various therapies.