Rare disease in children: the key role of a protein revealed

Professor Stéphane Lefrançois, a researcher at the Institut National de la Recherche Scientifique (INRS), is working on Batten disease, a neurodegenerative genetic disease that primarily affects children. His research focuses on the most common form of the disease -- Batten CLN 3 -- which is caused by mutations in the protein of the same name and for which there is still no cure. They recently published findings about a key role played by protein CLN3 in the Journal of Cell Science.