Researchers develop tools to sharpen 3D view of large RNA molecules

Scientists developed a method for generating high resolution 3D images of RNA, overcoming challenges limiting 3D analysis and imaging of RNA to only small molecules and pieces of RNA for the past 50 years. The new method, which expands the scope of nuclear magnetic resonance (NMR) spectroscopy, will enable researchers to understand the shape and structure of RNA molecules and learn how they interact with other molecules.