Researchers have identified a receptor, CD169 (also called Siglec1), that is exclusively expressed on macrophages and contributes to the hyper-inflammatory response of macrophages upon infection with SARS-CoV-2. These findings, they believe, may provide an explanation of how SARS-CoV-2 infection of macrophages in lungs of COVID-19 patients promote inflammatory responses.
Study uncovers mechanisms necessary for SARS-CoV-2 infection in macrophages
- ScienceDaily
- 24. 10 2022 (21:36)