Tiny biological package gets drug right to the 'heart' of transplant rejection

For patients who receive a heart transplant in the near future, the old adage, 'Good things come in small packages,' may become words to live by. In a recent study, researchers at Johns Hopkins Medicine and the National Cancer Institute (NCI) demonstrated in mice that they can easily deliver a promising anti-rejection drug directly to the area surrounding a grafted heart by packaging it within a tiny three-dimensional, protein gel cocoon known as a hydrogel.