Transplant drug sirolimus shrinks tumors, improves lung function

The drug sirolimus, normally used to help transplant patients fight organ rejection, may eventually be used as a less invasive treatment for a tumor called angiomyolipomata in patients with tuberous sclerosis complex or lymphangioleiomyomatosis who would otherwise face surgery. The finding is reported by investigators from Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine in the Jan. 10 edition of the New England Journal of Medicine.