Researchers at the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences have developed a catalytic system that directly installs the trifluoromethyl group onto arenes. The new reaction uses simple and abundant trifluoroacetic acid as the trifluoromethylating agent, and offers a milder alternative to the existing strategies.
Trifluoroacetic acid acts as trifluoromethylating agent in arene C-H functionalization
- PhysOrg
- 5. 8 2020 (18:50)