Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.

Mice exposed to the opioid oxycodone before birth experience permanent changes in behavior and gene expression. The new research published in eNeuro highlights a need to develop safer types of painkillers for pregnant women.

Two drugs commonly used to treat high blood pressure are equally effective as single-drug therapies, but one is slightly safer, a new study has found.

Canada should anticipate a resurgence of a childhood respiratory virus as COVID-19 physical distancing measures are relaxed, authors warn in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210919.

A new survey led by The Ohio State University's Office of the Chief Wellness Officer finds students are excited to get back to campus after a long and difficult year. But the trauma of the pandemic is still affecting their mental health. The survey found anxiety, depression and burnout are all on the rise among students, even as they find normalcy again. Those issues have also led to increases in...

The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can't recognize that without guidance from the hippocampus, according to a new study by neuroscientists at MIT's Picower Institute for Learning and Memory.

What The Study Did: The association between Medicare eligibility at age 65 and changes in racial and ethnic disparities in access to care and self-reported health was evaluated in this study.

A research team in the Korea Institute of Science and Technology(KIST) has announced the development of a thermal-imaging sensor that overcomes the existing problems of price and operating-temperature limitations. The sensor developed in this work can operate at temperatures upto 100 °C without a cooling device and is expected to be more affordable than standard sensors on the market, which...

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

Even in the absence of bark beetle outbreaks and wildfire, trees in Colorado subalpine forests are dying at increasing rates from warmer and drier summer conditions, found recent University of Colorado Boulder research.

Adolescents who set goals for their future and those with strong parental support are less likely to use e-cigarettes and other tobacco products, according to a new survey of nearly 2,500 high school students. The findings suggests that strategies to prevent youth vaping may be different from what works to dissuade youth from smoking cigarettes.

Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's Association International Conference® (AAIC®) 2021 in Denver, Colorado, and virtually.

Scientists around the world are collaborating on a project that is changing the way they trace the evolutionary history of flowering plants. By using new technology allowing them to rapidly retrieve and compare DNA sequences from among any of the 300,000 species of flowering plants, scientists are unraveling the 140-million-year history of the largest group of land plants on Earth and providing a...

There is an urgent need to develop and implement effective screening, diagnosis and treatment strategies for patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), common liver conditions with a rising burden in the U.S. and globally. This is particularly important for the most at-risk patients, those with diabetes and obesity.

A genetic analysis of fruit in the mandarin family has unraveled a complex journey from the mountainous region of southern China to the markets of Okinawa, says researchers from the Okinawa Institute of Science and Technology Graduate University.

People who trust science are more likely to believe and disseminate false claims containing scientific references than people who do not trust science, a study finds. Reminding people of the value of critical evaluation reduces belief in false claims, but reminding them of the value of trusting science does not.

New research has identified potential treatment that could improve the human immune system's ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate the immune system, which in turn can unleash other immune cells to attack tumours in cancer patients.

Survival rates for adolescents and young adults diagnosed with cancer have varied considerably depending on cancer type. A new study indicates that survival for multiple cancer types in such patients has improved in recent years, but some patients diagnosed with common cancer types still show limited survival improvements. The results are published by Wiley early online in CANCER, a peer-reviewed...

Historically marginalized racial and ethnic groups and Indigenous peoples have significant cardiovascular health inequities, and these groups are underrepresented in genetic and genomic research.Almost 80% of participants in genomic research are of European ancestry, yet this group makes up just 16% of the global population.Heart-disease risk calculations and information about how different...

Taken together these Oncotarget findings show that the CTD and OD domains of mtp53 R273H play critical roles in mutant p53 GOF that pertain to processes associated with DNA replication.

This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of the gliomas.

An international team of researchers from the Max Planck Institute for Plant Breeding Research and the University of Åarhus in Denmark have discovered that bacteria from the plant microbiota are adapted to their host species. In a newly published study, they show how root-associated bacteria have a competitive advantage when colonizing their native host, which allows them to invade an already...

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in Recent ultra-rare inherited variants implicate new autism candidate risk genes, a new study published in...

What The Study Did: Researchers examined the safety of the second dose of the Pfizer-BioNTech or Moderna COVID-19 vaccines in patients who experienced an allergic reaction to the first dose.