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'Obscurins' in breast tissue may help physicians predict and detect breast cancer

A new discovery published in the FASEB Journal may help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers explain how proteins, called "obscurins," thought only be in muscle cells, act as "tumor suppressor genes" in the breast. When their expression is lost, or their genes mutated in breast epithelial cells, cancer develops. It promises to tell...

20-year results from breast cancer screening program show a significant drop in deaths, limited harm and reasonable costs

Results from the Dutch national breast cancer screening program, one of longest-running national screening programs in the world, have shown that it has contributed to a drop in deaths from the disease, that any harm caused by the screening, such as false positives and over-diagnosis, has been limited, and that the costs have been reasonable. Compared with the pre-screening period 1986 to 1988,...

A structured, independent exercise regimen can reduce the need for therapy

The treatment of meniscus tears in injured workers is associated with less favorable outcomes and higher utilization of clinical services. "Disability, Impairment, and Physical Therapy Utilization in Workers' Compensation Patients after Arthroscopic Partial Meniscectomy," is a study appearing in the March 21, 2012, issue of the JBJS, which investigates the effects of a recommended, self-regulated...

As industry funding for medical education fades, new opportunities for improvements arise

Public scrutiny and the threat of government regulation are leading to a decline in industry-sponsored funding of accredited continuing medical education (CME) for physicians, and this decline represents an opportunity to make CME more relevant, cost-effective and less open to bias, wrote a group of physicians from the San Francisco VA Medical Center and the University of California, San...

Berkeley Lab study shows far higher potential for wind energy in India than previously estimated

A new assessment of wind energy in India by Lawrence Berkeley National Laboratory has found that the potential for on-shore wind energy deployment is far higher than the official estimates -- about 20 times and up to 30 times greater than the current government estimate of 102 gigawatts. This landmark finding may have significant impact on India's renewable energy strategy as it attempts to cope...

Brain's involvement in processing depends on language's graphic symbols

Readers whose mother tongue is Arabic have more challenges reading in Arabic than native Hebrew or English speakers have reading their native languages, because the two halves of the brain divide the labor differently when the brain processes Arabic than when it processes Hebrew or English. That is the result of a new study conducted by University of Haifa researchers.

Breast cancer screening and better treatment both help to save significant numbers of lives

A Dutch study of the effectiveness of breast cancer screening shows that, even with improved treatments for the disease, population-based mammography programs still save a significant number of lives. The researchers found that adjuvant therapy (treatment given in addition to primary therapy such as surgery) reduced deaths by an estimated 13.9 percent in 2008 compared to no treatment; but they...

Bronchoscopy can guide effective treatment for refractory asthma

Using a bronchoscope to visually examine the airways and collect fluid and tissue can help guide effective therapy for difficult-to-treat asthma patients, according to researchers at National Jewish Health. The researchers identified five distinct phenotypes among the refractory asthma patients, and successfully treated four of them, often with reduced asthma medications. "Bronchoscopy provides...