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Cancer cells in blood predict chances of survival and can help target breast cancer treatment

German doctors have found that breast cancer patients with at least five circulating tumor cells in their blood detected straight after surgery have a four-fold increase in the risk of recurrence and a three-fold increase in the risk of death. In addition to helping provide a more accurate evaluation of disease outcome, CTCs might also become targets for treatment in the future, they say.

Challenges in salivary diagnostics

On March 22, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research, a symposium titled "Challenges in Salivary Diagnostics" will take place to discuss the issues with saliva collection and storage, proteomic analyses, and the growing interest and availability of commercial tests for salivary biomarkers.

Composite PVC materials with enhanced thermal stability on the basis of nanofillings

Researchers at the Public University of Navarre are working on a project to design and manufacture composite PVC materials based on nanofillings and intended for multi-sectoral applications. The ultimate aim of the Vinilclay project is to control and optimize the properties of the plastic material; specifically, its photostability, thermal resistance and gas permeation.

Computer model of spread of dementia can predict future disease patterns years before they occur

Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all...

Dense breasts can nearly double the risk of breast cancer recurrence

Women aged 50 and over with breasts that have a high percentage of dense tissue are at greater risk of their breast cancer recurring, according to researchers from Sweden. They found that women with denser breasts had nearly double the risk of their cancer recurring, either in the same breast or in the surrounding lymph nodes, than women with less dense breasts.

Diet may be affecting rhino reproduction

Southern white rhinoceros populations, once thriving in zoos, have been showing severely reduced reproductivity among the captive-born population. San Diego Zoo Global researchers have a possible lead into why the southern white rhinoceros population in managed-care facilities is declining: phytoestrogens in their diet might be contributing to reproductive failure in the females.

Discovery offers insight into treating viral stomach flu

While researchers say that vaccines for intestinal infections are among the most difficult to develop, a recent discovery may provide the critical information needed for success. "Sometimes atomic structure gives us clues on how viruses work and how to make better vaccines," said Dr. Thomas Smith, principal investigator, at the Donald Danforth Plant Science Center.

Energy requirements make Antarctic fur seal pups vulnerable to climate change

A study published in the journal Physiological and Biochemical Zoology found that changing weather conditions can impact the metabolic rates of fur seal pups. Climate models predict windier and wetter conditions in Antarctica in the coming years, and that could cause young seals to assign more energy to thermoregulation, leaving less available for growth and development.

Genetic mutation found in familial chronic diarrhea syndrome

When the intestines are not able to properly process our diet, a variety of disorders can develop, with chronic diarrhea as a common symptom. Chronic diarrhea can also be inherited, most commonly through conditions with genetic components such as irritable bowel syndrome. Researchers in Norway, India, and at the HudsonAlpha Institute for Biotechnology have identified one heritable DNA mutation...

Geosphere's dynamic platform displays the latest 3-D modeling, LiDAR imaging, and more

Highlights include new entries to the special issues "Seeing the True Shape of Earth's Surface" and "Origin and Evolution of the Sierra Nevada and Walker Lane." Also online: 3-D modeling of the area in the Pacific Ring of Fire affected by the magnitude 8.1 earthquake on 29 Sept.; another article comparing three different 3-D modeling software packages; and the identification of ancient marine...

Have I got cancer or haven't I? Medical staff confuse women with ductal carcinoma in situ

Women diagnosed with ductal carcinoma in situ need clear communication and tailored support to enable them to understand this complex breast condition, which has divided the medical profession when it comes to its perception and prognosis. Researchers who spoke to 45 women found that many were very confused about whether or not they had cancer and that medical staff often added to this confusion...

Hospitalization associated with increased cognitive decline in older adults

A new study published in the March 21 issue of Neurology suggests that older adults who are hospitalized may have an increased risk of subsequent cognitive decline. The study, conducted by researchers at the Rush Alzheimer's Disease Center and the Rush Institute for Healthy Aging, Rush University Medical Center, found that hospitalization of older adults was associated with increased memory and...

How the alphabet of data processing is growing: Research team generates flying 'qubits'

The alphabet of data processing could include more elements than the "0" and "1" in future. An international research team has achieved a new kind of bit with single electrons, called quantum bits, or qubits. With them, considerably more than two states can be defined. So far, quantum bits have only existed in relatively large vacuum chambers. The team has now generated them in semiconductors.

Keeping track to selenium metabolism

Spanish and Danish researchers have developed a method for the in vivo study of the unknown metabolism of selenium, an essential element for living beings. The technique can help clarify whether or not it possesses the anti-tumor properties that have been attributed to it and yet have not been verified through clinical trials.

Key to immune system disease could lie inside the cheek

Cardiff University scientists have produced powerful new cells which can suppress the body's immune system. The cells are obtained by cloning tissue lining the human cheek, a less invasive process than obtaining adult stem cells from bone marrow. The breakthrough offers long term hope for dealing with immune system disorders.