878,398 articles

First Wave Of Swine Flu Hit Young People Harder Than Expected

A mathematical epidemiologist is researching the A(H1N1) influenza pandemic strain circulating around the world. The new study's findings reveal an age shift in the proportion of cases toward a younger population when compared with historical patterns of seasonal influenza in Mexico. "For the 1918 ("Spanish flu") influenza pandemic, this was the pattern -- first a mild wave, and then a severe one...

Researchers Unveil Whiskered Robot Rat

Scientists have developed an innovative robot rat which can seek out and identify objects using its whiskers. The SCRATCHbot robot will be demonstrated at an international workshop looking at how robots can help us examine the workings of the brain.

Clocking Salt Levels In The Blood: Link Between The Circadian Rhythm And Salt Balance

New research suggests a link between the circadian rhythm and control of sodium (salt) levels in the blood of mice. Specifically, the circadian clock protein Period 1 was found to function downstream of the hormone aldosterone (a known controller of blood sodium levels and thereby blood pressure) to regulate levels of the alpha-subunit of the epithelial sodium channel in the mouse...

No Evidence That WHO-recommended Treatment For Insecticide Poisoning Improves Survival

A new study finds no evidence to suggest that a controversial antidote recommended by the World Health Organization (WHO) to treat patients poisoned with highly toxic insecticides improves their chance of survival. The results may even add weight to existing concerns about pralidoxime, the treatment recommended by the WHO, by suggesting that it could be harmful in patients who have deliberately...

Avian Bacterium More Dangerous Than Believed

Bordetella hinzii just may be the Eddie Haskell of avian bacteria. Like the notoriously sneaky character from the iconic 1950s television show "Leave It to Beaver," B. hinzii has been causing trouble and dodging the blame.

Caffeine reverses memory impairment in Alzheimer's mice

Coffee drinkers may have another reason to pour that extra cup. When aged mice bred to develop symptoms of Alzheimer's disease were given caffeine -- the equivalent of five cups of coffee a day -- their memory impairment was reversed, report researchers at the Florida Alzheimer's Disease Research Center.

DNA variations linked to brain tumors

Mayo Clinic researchers and colleagues at the University of California San Francisco have found a connection between DNA alterations on human chromosome 9 and aggressive brain cancer known as glioblastoma.

Genetic Factors That Hold Promise For Treatment Of Vascular Diseases

Researchers have discovered a key switch that makes stem cells turn into the type of muscle cells that reside in the wall of blood vessels. The same switch might be used in the future to limit growth of vascular muscle cells that cause narrowing of arteries leading to heart attacks and strokes, limit formation of blood vessels that feed cancers or make new blood vessels for organs that are not...

Gladstone scientists identify genetic factors that hold promise for treatment of vascular diseases

Researchers at the Gladstone Institute of Cardiovascular Disease have discovered a key switch that makes stem cells turn into the type of muscle cells that reside in the wall of blood vessels. The same switch might be used in the future to limit growth of vascular muscle cells that cause narrowing of arteries leading to heart attacks and strokes, limit formation of blood vessels that feed cancers...

GUMC discovery highlights new direction for drug discovery

In a discovery that rebuffs conventional scientific thinking, researchers at Georgetown University Medical Center have discovered a novel way to block the activity of the fusion protein responsible for Ewing's sarcoma, a rare cancer found in children and young adults.

Molecule That Regulates Heart Size Developed By Using Zebrafish Screening Model

Using zebrafish, researchers have identified and described an enzyme inhibitor that increases the number of cardiac progenitor cells and influences the size of the developing heart. The task was accomplished primarily because of the powerful advantages of studying embryonic development in zebrafish, vertebrates whose transparent embryos develop rapidly, are small and easy to handle and, most...

Pitt team finds molecule that regulates heart size by using zebrafish screening model

Using zebrafish, researchers at the University of Pittsburgh have identified and described in Nature Chemical Biology an enzyme inhibitor that increases the number of cardiac progenitor cells and influences the size of the developing heart. The task was accomplished primarily because of the powerful advantages of studying embryonic development in zebrafish, vertebrates whose transparent embryos...

The GenoMEL project identifies a new region of the genome associated with the risk of melanoma

The genetic study includes 1650 patients and 4336 control subjects from Europe and Australia. Of the three regions of the genome with small variations identified as risk factors for melanoma, one is new and two are associated with pigmentation. These risk factors are shared despite genetic variability and differences in exposure to sunlight in the countries represented in the study. IDIBAPS --...