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151,290 articles from ScienceDaily

'Sting' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

In studies with mouse and human tissue, as well as live mice, researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease. Specifically, the researchers found that a protein dubbed 'STING' responds to clean-up signals in brain cells damaged by Parkinson's disease by creating a cycle of inflammation that may...

Researchers find another layer to the code of life

A new examination of the way different tissues read information from genes has discovered that the brain and testes appear to be extraordinarily open to the use of rare codons to produce a given protein. Testes of both fruit flies and humans seem to be enriched in protein products of these rarely-used pieces of genetic code, suggesting another layer of control in the genome.

How a cognitive bias is blocking the rise of electric cars

What are the barriers to the adoption of electric cars? Although the main financial and technological obstacles have been removed, their market share still needs to increase. In a recent study, a team investigated the cognitive factors that still dissuade many people from switching to electric cars. They found that car owners systematically underestimate the capacity of electric driving ranges to...

New process revolutionizes microfluidic fabrication

Microfluidic devices use tiny spaces to manipulate very small quantities of liquids and gasses by taking advantage of the properties they exhibit at the microscale. They have demonstrated usefulness in applications from inkjet printing to chemical analysis and have great potential in personal medicine, where they can miniaturize many tests that now require a full lab, lending them the name...

Music alleviates collective grief

In February 2020, a group of musicians from around the world living in China recorded their cover of a song by Michael Jackson on video to express their support to the families affected by the COVID-19 pandemic and to those working in the frontline. The video went viral. Now, a new study analyzes why the video and song had such a profound effect.

how one of the X chromosomes in female embryonic stem cells is silenced

In most mammals, females have two X chromosomes and males have one X and one Y chromosome in each of their cells. To avoid a double dose of X-linked genes in females, one of the Xs is silenced early in the developmental process. This silencing is critical, yet how it happens has been relatively mysterious. Two new studies reveal more about this silencing process and insights that could improve...

New thermal management technology for electronic devices reduces bulk while improving cooling

Electronic devices generate heat, and that heat must be dissipated. The high temperatures can compromise device function or even damage the devices and surroundings if it isn't. Now, a team has detailed a new cooling method that offers a host of benefits, not the least of which is space efficiency which offers a substantial increase over conventional approaches in devices' power per unit volume.

Watch dolphins line up to self-medicate skin ailments at coral 'clinics'

If a human comes down with a rash, they might go to the doctor and come away with some ointment to put on it. Indo-Pacific bottlenose dolphins get skin conditions, too, but they come about their medication by queuing up nose-to-tail to rub themselves against corals. Researchers now show that these corals have medicinal properties, suggesting that the dolphins are using the marine invertebrates to...

New study shows genes can predict response to arthritis treatment and paves the way for future drug development

New research has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients. The researchers also identified specific genes associated with resistance to most available drugs therapies, commonly referred to as refractory disease, which could provide the key to developing new, successful...

Broadening the scope of epoxide ring opening reactions with zirconocene

Epoxide, a cyclic ether, can be used to obtain important alcohols, pharmaceuticals, agrochemicals, and functional polymers. This transformation is facilitated by the reductive ring opening of epoxide. Traditionally, the reaction has been catalyzed using titanocene. However, in this case, the products are predominantly obtained via more stable radicals. Now, chemists turn the tables and broaden the...

Cooperation rewards water utilities

Inter-utility water agreements can help mitigate risks, in research that used supercomputer simulations of water supply in the North Carolina Research Triangle. Findings are generalizable to any place where water providers face financial and supply challenges in allocating regional water.