Researchers have developed a new DNA-nanotechnology-based approach called Immuno-SABER, that combines the protein targeting specificity of commonly available antibodies with a DNA-based signal-amplification strategy that enables the highly multiplexed visualization of many proteins in the same sample with pre-programmable and tunable fluorescence signals at each target site.

Using a cellphone to take a break during mentally challenging tasks does not allow the brain to recharge effectively and may result in poorer performance, researchers found.

Computer models show why eruptive magma chambers tend to reside between six and 10 kilometers underground.

A newly created biologically inspired compound eye is helping scientists understand how insects use their compound eyes to sense an object and its trajectory with such speed. The compound eye could also be used with a camera to create 3D location systems for robots, self-driving cars and unmanned aerial vehicles.

Every day, people are exposed to myriad chemicals both natural and synthetic, some of which may affect human physical development. Researchers have discovered nacq#1, a natural compound produced by a soil roundworm that dramatically influences time to sexual maturity and lifespan in tiny amounts. Because nacq#1 and its related nuclear receptors are so similar between the worm and humans, miniscule...

Study provides new evidence of synergistic effects of drugs that inhibit cell division and support for further clinical trials.

Children with a high genetic risk of developing type 1 diabetes have different gut microbiomes than children with a low risk, according to a new study. The results suggest that genetic risk can shape an individual's response to environmental factors in the development of autoimmune diseases.

Researchers have created a quantum spin wave for light. This can be a carrier of information for future nanotechnologies but with a unique twist: they only flow in one direction.

River diversions have not created or maintained land, but resulted in more land loss, according to a new article.

A team of astronomers has discovered a second giant planet in orbit around alpha Pictoris, a star that is relatively young (23 million years old) and close (63.4 light years), and surrounded by a disk of dust. The alpha Pictoris system has fascinated astronomers for the last 30 years since it enables them to observe a planetary system in the process of forming around its star.

Scientists are investigating new ways to provide visual signals to the blind by directly stimulating the optic nerve. Their preliminary study uses a new type of neural electrode and provides distinct signals.

Scientists have carried out an analysis of long-term data of an outbreak of classical swine fever in wild boars in the German federal state of Mecklenburg-Vorpommern that occurred between 1993 and 2000. The results show that non-infected regions have a higher risk of infection due to changes in movement patterns, particularly during the mast and rutting seasons (autumn and winter).

T cell immunotherapy uses the immune system to kill cancer cells. To increase the efficacy of this new treatment, researchers aimed to discover a master regulator of T cell fate. The signaling lipid sphingosine 1-phosphate (S1P) influences the T cell lineage: high levels of S1P lead to an inhibitory regulatory T cell phenotype, while low levels of S1P lead to a central memory-like phenotype, which...

In a recently published study examining the effects of binge drinking on rats, researchers discovered that female rats who were of equal age and weight to male rats were more sensitive to alcohol and experienced alcoholic liver injury at a higher rate than male rats.

Scientists have designed organic molecules capable of generating two excitons per photon of light, a process called singlet fission. The excitons can live for much longer than those generated from their inorganic counterparts, which leads to an amplification of electricity generated per photon that is absorbed by a solar cell.

Researchers believe that stuttering -- a potentially lifelong and debilitating speech disorder -- stems from problems with the circuits in the brain that control speech, but precisely how and where these problems occur is unknown. Using a mouse model of stuttering, scientists report that a loss of cells in the brain called astrocytes are associated with stuttering. The mice had been engineered...

The liver plays a vital role as a filter in the body. But what happens when it malfunctions? Researchers performed a detailed analysis of hepatic encephalopathy. The scientists were able to observe for the first time in a mouse model that a dysfunction of the liver provokes cerebral molecular disturbances in two weeks, even though no physical symptoms are apparent. Moreover, several molecules are...

National or other emissions inventories of greenhouse gases that are used to develop strategies and track progress in terms of emissions reductions for climate mitigation contain a certain amount of uncertainty, which inevitably has an impact on the decisions they inform. Researchers contributed to several studies in a recently published volume that aims to enhance understanding of uncertainty in...

The existence of water in deep Earth is considered to play an important role in geodynamics, because water drastically changes the physical properties of mantle rock, such as melting temperature, electric conductivity, and rheological properties. Water is transported into deep Earth by the hydrous minerals in the subducting cold plates. Hydrous minerals, such as serpentine, mica and clay minerals,...

Adults who have experienced maltreatment as children have a changed perception of social stimuli. Traumatized people found touch stimuli less comforting than people who had not experienced trauma. They also maintained a greater social distance from strangers. In addition, the researchers discovered changes in the activation of certain brain areas.

An experiment to test a popular theory of dark energy has found no evidence of new forces, placing strong constraints on related theories.

Scientists have developed an innovative, electrohydraulically actuated valve train for internal combustion engines, that enables completely free adjustment of stroke and timing, while at the same time being robust and cost effective. This valve train was mounted on a serial production engine and has been running successfully for several months. The new technology saves up to 20% fuel.

To a large extent, DNA methylation, which regulates vital cell functions, is still a big mystery to the scientific world. Now,, scientists have developed a method to quickly couple methylation enzymes to their respective methylation pattern. This finding could become essential for successful gene engineering in many species.

Researchers have conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma (GBM), proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an original Japanese cohort and a dataset from The Cancer Genome Atlas (TCGA).