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19 articles from ScienceDaily

Art of printing extremely hard steels flawlessly

For millennia, metallurgists have been meticulously tweaking the ingredients of steel to enhance its properties. As a result, several variants of steel exist today; but one type, called martensitic steel, stands out from its steel cousins as stronger and more cost-effective to produce. Hence, martensitic steels naturally lend themselves to applications in the aerospace, automotive and defense...

Nanoparticles: Acidic alert

Researchers have synthesized nanoparticles that can be induced by a change in pH to release a deadly dose of ionized iron within cells. This mechanism could potentially open up new approaches to the targeted elimination of malignant tumors.

New discovery settles long-standing debate about photovoltaic materials

Scientists have theorized that organometallic halide perovskites -- a class of light harvesting 'wonder' materials for applications in solar cells and quantum electronics -- are so promising due to an unseen yet highly controversial mechanism called the Rashba effect. Scientists have now experimentally proven the existence of the effect in bulk perovskites.

Simulations show how to make gene therapy more effective

Diseases with a genetic cause could be treated by supplying a correct version of the faulty gene. However, in practice, delivering new genetic material to human cells is difficult. A promising method for the delivery of such genes involves the use of DNA/lipid complexes (lipoplexes). Scientists have now used advanced simulations to investigate how these lipoplexes deliver DNA fragments into cells....

Cell biology: Your number's up!

mRNAs program the synthesis of proteins in cells, and their functional lifetimes are dynamically regulated. Researchers have now shown why blueprints that are more difficult to decipher have shorter lifetimes than others.

Cancer drug resistance study raises immune red flags

Once a cancer patient's tumors develop resistance to chemotherapy, the prognosis can be poor. However, inhibiting a key gene involved in multidrug resistance, MDR1, has not improved outcomes. A new study offers a reason, revealing unintended downstream effects on immune system cells.

Under pressure: New bioinspired material can 'shapeshift' to external forces

Inspired by how human bone and colorful coral reefs adjust mineral deposits in response to their surrounding environments, researchers have created a self-adapting material that can change its stiffness in response to the applied force. This advancement can someday open the doors for materials that can self-reinforce to prepare for increased force or stop further damage.

Nasal smear as an allergy screening test

In the world of allergy diagnostics, the familiar blood samples and unpleasant skin prick procedures for testing allergen tolerance may soon be a thing of the past. A team of researchers has demonstrated that sufficient quantities of allergy antibodies for a diagnosis can be effectively measured in nasal secretions.

New chemical tools can control the concentration of lipids in living cells

So far, it has been difficult to analyze the functions of lipid molecules in living cells. Researchers have now developed chemical tools that can be activated by light and used to influence lipid concentration in living cells. This approach could enable medical doctors to work with biochemists to identify what molecules within a cell do.