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72 articles from ScienceDaily

Researchers develop a yeast-based platform to boost production of rare natural molecules

Researchers outline a method to synthesize complex bioactive molecules much more quickly and efficiently. Using cutting-edge synthetic biology approaches, They were able to produce a large amount of benzylisoquinoline alkaloid (BIA) to synthesize an array of natural and new-to-nature chemical structures in a yeast-based platform. This can provide a blueprint for the large-scale production of...

Genetics of the tree of life

Baobab trees can live for more than a thousand years and provide food, livestock fodder, medicinal compounds, and raw materials. Scientists counted the significant tree's chromosomes -- information critical for conservation, agricultural improvement, and further genetic work.

DNA repair: Locating and severing lethal links

Covalent cross-links between proteins and DNA are among the most hazardous types of DNA damage. Researchers have now characterized an enzyme that breaks such bonds, and elucidated how it specifically recognizes sites of damage.

Helminth infections common in Medieval Europe, grave study finds

Although helminth infections -- including tapeworms and roundworms -- are among the world's top neglected diseases, they are no longer endemic in Europe. However, researchers report that these infections were common in Medieval Europe, according to grave samples analyzed from across the continent.

Synthetic compound could serve as prototype for novel class of drugs to treat neurological damage

Researchers have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms of certain neurological injuries and diseases, while on the microscopic level it was able to establish and repair connections between neurons. This proof-of-principle study suggests that biologics, which act on neuronal connectivity, could be of...

A new method for making a key component of plastics

Scientists have discovered a previously unknown way that some bacteria produce the chemical ethylene - a finding that could lead to new ways to produce plastics without using fossil fuels. The study showed that the bacteria created ethylene gas as a byproduct of metabolizing sulfur, which they need to survive.

The Le Teil earthquake provides new insights on seismic risk in France and Western Europe

On 11 November 2019, a magnitude 5 earthquake occurred near the village of Le Teil in the Rhône River Valley in southern France producing an unexpected surface rupture with ground displacement. For the first time in France, scientists had the opportunity to use all modern seismological, geodetical, and geological techniques available to study this historically unprecedented seismic event.

Prior Zika virus infection increases risk of severe dengue disease

A new study finds that people who have antibodies to the mosquito-borne Zika virus are more vulnerable to developing dengue disease. This immune interaction, called antibody-dependent enhancement, could complicate the search for a safe and effective vaccine that protects against Zika without also increasing the risk of dengue.

Mosquito immune system mapped to help fight malaria

Scientists have created the first cell atlas of mosquito immune cells, to understand how mosquitoes fight malaria and other infections. Researchers discovered new types of mosquito immune cells, including a rare cell type that could be involved in limiting malaria infection. The findings offer opportunities for uncovering novel ways to prevent mosquitoes from spreading the malaria parasite to...