A team of researchers has uncovered key molecular step stones in ALD that may provide targets for drug therapy development.

Even a small change may cause long-term consequences. For amyloid beta peptides, a major hallmark of Alzheimer's disease, a common chemical modification at a particular location on the molecule has a butterfly effect that leads to protein misfolding, aggregation and cellular toxicity.

Discussions of drought often center on the lack of precipitation. But among climate scientists, the focus is shifting to include the growing role that warming temperatures are playing as potent drivers of greater aridity and drought intensification.

By studying the chemical elements on Mars today -- including carbon and oxygen -- scientists can work backwards to piece together the history of a planet that once had the conditions necessary to support life.

Scientists are using light waves to accelerate supercurrents to access the unique and potentially useful properties of the quantum world.

A landmark review of the role of artificial intelligence (AI) in the future of global health calls on the global health community to establish guidelines for development and deployment of new technologies and to develop a human-centered research agenda to facilitate equitable and ethical use of AI.

A new study finds that our mental health and mortality have a strong correlation with the amount of autonomy we have at our job, our workload and job demands, and our cognitive ability to deal with those demands.

A paleontologist visiting the Natural History Museum in London desperately wanted a good look at the skeleton of an extinct aquatic reptile, but its glass case was too far up the wall. So he attached his digital camera to a fishing rod and -- with several clicks -- snagged a big one, scientifically speaking.

Call them 'super polluters' -- the handful of industrial facilities that emit unusually high levels of toxic chemical pollution year after year. There are only a few of them, but together they account for the majority of annual industrial pollution.

A major transformation in vertebrate evolution took place when breathing shifted from being driven by head and throat muscles -- like in fish and frogs -- to the torso -- like in reptiles and mammals. But what caused the shift? A new study posits that the intermediate step was locomotion. When lizards walk, they bend side-to-side. The ribs and vertebrae are crucial to this movement, and the...

This odd behavior may promote the material's ability upon cooling to perfectly conduct electricity in a way unexplained by standard theories.

Scientists working at Caesar have developed a small head-mounted microscope that allows access to the inner workings of the brain. The new system enables measurement of activity from neuronal populations located in the deep cortical layer with single-cell resolution, in an animal that is freely behaving.

Seeing someone do something good for someone else motivates witnesses to perform their own helpful acts, an insight that could help drive cooperative behavior in communities navigating through the health crisis.

The challenge of diversifying STEM fields may get a boost from the results of a new study that show field courses help build self-confidence among students -- especially those from underrepresented groups.

A new study looked at US tax policy as it relates to carbon dioxide (CO2), from 2015 through 2030. The study found only limited short-term opportunities for decarbonization (reducing greenhouse gas emissions) outside the electricity sector. The result is substantial CO2 tax revenue. The findings shed light on future tax policy decisions.

Researchers have identified small molecules in the blood of asymptomatic pregnant women that may predict risk for preeclampsia, responsible for a significant proportion of maternal and neonatal deaths, low birth weight and is a primary cause of premature birth.

As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, mitochondria decline with age not only in humans, but in many species. Why they do so is not well understood. Scientists set out to understand how mitochondrial function is...

Palm oil is often associated with tropical deforestation above all else. However, this is only one side of the story, as agricultural scientists show in a new study. The rapid expansion of oil palm has also contributed considerably to economic growth and poverty reduction in local communities, particularly in Asia.

Connected and automated vehicles use technology such as sensors, cameras and advanced control algorithms to adjust their operation to changing conditions with little or no input from drivers. A research group optimized vehicle dynamics and powertrain operation using connectivity and automation, while developing and testing a control framework that reduced travel time and energy use in a connected...

Scientists engineering valuable microbes for renewable fuels and bioproducts have developed an efficient way to identify the most promising varieties. Researchers have developed a high-throughput screening technique to rapidly profile medium-chain fatty acids produced in yeast -- part of a larger group of free fatty acids that are key components in essential nutrients, soaps, industrial chemicals,...

To better understand and mitigate the health risks faced by astronauts from exposure to space radiation, we ideally need to be able to test the effects of galactic cosmic rays (GCRs) here on Earth under laboratory conditions.

Scientists have developed a highly printable bioink as a platform to generate anatomical-scale functional tissues.

When it comes to future food production, the combined farming of fish and vegetables through aquaponics is currently a hotly debated topic. But how realistic is the idea? Researchers have just published an extensive profitability analysis of a facility that already produces fish and vegetables on a large scale. The result: aquaponics may have both environmental and cost benefits -- if produced...

In a new study, researchers call attention to the emergence of mosquito-borne viral outbreaks in West Africa, such as dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses.