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57 articles from ScienceDaily

Researchers solve a long-standing problem in organic chemistry

Chemists have for a long time been interested in efficiently constructing polyenes - not least in order to be able to use them for future biomedical applications. However, such designs are currently neither simple nor inexpensive. Scientists have now found a bio-inspired solution to the problem.

About 94 per cent of wild bee and native plant species networks lost

Climate change and an increase in disturbed bee habitats from expanding agriculture and development in northeastern North America over the last 30 years are likely responsible for a 94 per cent loss of plant-pollinator networks, researchers found. The researchers looked at plant-pollinator networks from 125 years ago through present day.

Two paths of aging: New insights on promoting healthspan

Scientists have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan. Cells embark upon either a nucleolar or mitochondrial path early in life, and follow this ''aging route'' throughout their entire lifespan through decline and death. At the heart...

Megaphages harbor mini-Cas proteins ideal for gene editing

Cas proteins like CRISPR-Cas9 have great potential for gene therapy to treat human disease and for altering crop genes, but the gene-targeting and gene-cutting Cas proteins are often large and hard to ferry into cells with viral vectors such as adenovirus. Scientists have now discovered a hypercompact Cas protein, Cas-phi, that should work better. It is half the size of Cas9 and apparently evolved...

Evidence for decades-old theory to explain the odd behaviors of water

A new study provides strong evidence for a controversial theory that at very cold temperatures water can exist in two distinct liquid forms, one being less dense and more structured than the other. Researchers conducted computer simulations of water molecules to discover the critical point at the transition between the two forms.

Dangerous blood clots form in leg arteries of COVID-19 patients

COVID-19 is associated with life-threatening blood clots in the arteries of the legs, according to a new study. Researchers said COVID-19 patients with symptoms of inadequate blood supply to the lower extremities tend to have larger clots and a significantly higher rate of amputation and death than uninfected people with the same condition.