A potential new treatment for mast cell cancers reduces the number of mast cells by 'mutating' the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation. The method, known as frameshifting, changes the pre-mRNA so that the mature mRNA is degraded and any protein produced from its instructions is altered and inert. In a mouse model,...

Novel camera detects the birth of high-energy runaway electrons, which may lead to determining how to prevent damage caused by the highly energetic particles.

A new algorithm helps drones find the fastest route around obstacles without crashing. The system could enable fast, nimble drones for time-critical operations such as search and rescue.

A new study has presented and characterized the formation and properties of a superparamagnetic ring, which fits snugly around a drop of water due to liquid-liquid interaction, and allows the drops to be physically manipulated.

Researchers have found that people recovering from COVID-19 and those vaccinated against the causative virus, SARS-CoV-2, produce identical clones, or groups, of antibody-producing white blood cells.

A new machine learning approach helps scientists understand why extreme precipitation days in the Midwest are becoming more frequent. It could also help scientists better predict how these and other extreme weather events will change in the future.

Researchers have identified two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team may have found the 'Achilles' heel' of the virus, with potential for pan-variant therapeutic interventions.

The reefs at Palmyra Atoll, a small outlying atoll in the equatorial Pacific Ocean, have been undergoing a shift from stony corals to systems dominated by corallimorphs, marine invertebrates that share traits with both anemones and hard corals. Marine biology researchers discovered that although the invading corallimorph is the same species that has been there for decades, its appearance recently...

A global catastrophe 66 million years ago led to the extinction of all non-avian dinosaurs, and large marine reptiles like mosasaurs and plesiosaurs. But what happened to the sharks? According to a new study, shark-tooth diversity remained relatively constant across the mass extinction event at the end of the Cretaceous.

The NASA Dragonfly mission will send a rotorcraft relocatable lander to the surface of Saturn's moon Titan in the mid-2030s; it will be the first mission to explore the surface of Titan.

A team has succeeded in computing how atomic nuclei of the Calcium element behave in collisions with electrons. Results agree very well with available experimental data. For the first time, a calculation based on a fundamental theory is capable of correctly describing experiments for a nucleus as heavy as Calcium. Of particular relevance is the potential that such calculations could have in the...

Researchers have developed a platform which can quickly identify common mutations on the SARS-CoV-2 virus that allow it to escape antibodies and infect cells, which could inform the development of more effective booster vaccines and tailored antibody treatments for patients with COVID-19.

Healthy skin has a bacterial shield to protect against germs: the microbiome. This complex assembly of microorganisms was previously believed to be difficult to decipher. A team of researchers has now succeeded in using the enzyme benzonase to identify the living bacteria in skin swabs through sequencing. Their method opens up new possibilities for diagnosis and treatment in dermatology.

Researchers are proposing a new way to modulate both the absorptive and the refractive qualities of metamaterials in real time, and their findings open intriguing new opportunities to control, in time and space, the propagation and scattering of waves for applications in various areas of wave physics and engineering.

Imagine if you could attach something to your skin without needing glue. A biosensor, a watch, a communications device, a fashion accessory -- the possibilities are endless. Thanks to a discovery, that time could be closer than you think.

A new study offers an outline of the requirements and research challenges involved in designing effective policies to meet sustainability goals for cities.

Darwin's finches on the Galápagos Islands are once again providing insights into the theory of evolution, with two studies investigating their dealings with the parasitic avian vampire fly (Philornis downsi). One study investigated which species of finch proved to be the most successful hosts for the flies, while a second study looked at how the birds cope with being infected by the parasites....

Phosphate glasses are expected to have applications in a variety of fields. To improve their functionality, it is necessary to determine the association between their structure and ion diffusion characteristics. Recently, using first-principles molecular dynamic simulations, researchers have provided novel insights into the ion diffusion mechanisms of phosphate glass, suggesting that ionic...

Workplace incivility is on the rise, and a new study found that employees who experience or witness incivilities are more likely to be uncivil to others -- a worrying trend that could intensify as people return to in-person work.

Results from two decades of data show ultraprocessed foods have become a larger part of kids' and teens' diets with disparities by race and ethnicity.

A preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. Valve loss or dysfunction that disrupts the flow of lymph fluid is strongly associated with lymphedema in patients. But no one has discovered whether new valves can be grown or if defective ones can be fixed. The new study, using a model of human primary lymphedema, shows that both...

Researchers review recent scientific literature about the effects of particle contaminants on the mucosal system, an internal membrane that serves as the body's lubricant and the first line of defense from infections and toxins. These data establish a clear link between exposure to airborne or waterborne particulate matter and several health conditions.

Increased air pollution in recent years has exacerbated health risks for people who suffer from pulmonary diseases and these dynamics underscore the importance of increasing the efficacy of drug delivery devices that administer active pharmaceutical ingredients to treat respiratory illnesses. Researchers describe developing a computational evaluation of drug delivery through both pressurized...

It is well known that fat cells can influence our sensitivity to insulin. Now, researchers have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes.