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986 articles from ScienceDaily

Not just for finding planets: Exoplanet-hunter TESS telescope spots bright gamma-ray burst

NASA has a long tradition of unexpected discoveries, and the space program's TESS mission is no different. Astrophysicists have discovered a particularly bright gamma-ray burst using a NASA telescope designed to find exoplanets - those occurring outside our solar system - particularly those that might be able to support life. It's the first time a gamma-ray burst has been found this way.

Engineering T cells to attack cancer broadly

This study builds on decades of work showing that the protein IL-24 attacks cancer broadly, and is the first to deliver the protein using T cells. This approach is in contrast to CAR-T cells, which are built to recognize proteins on the surface of cancer cells and haven't been successful against solid tumors. Mice with prostate cancer experienced shrinkage of the original tumor as well as distant...

Move over CRISPR, the Retrons are coming

Researchers have created a new gene editing tool called Retron Library Recombineering (RLR) that can generate up to millions of mutations simultaneously, and 'barcodes' mutant bacterial cells so that the entire pool can be screened at once. It can be used in contexts where CRISPR is toxic or not feasible, and results in better editing rates.

Novel coronavirus' spike protein plays additional key role in illness

A new study shows that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19's wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.

Light as a fairy tale: What makes a feel-good film feel good?

'Feel-good films' are usually dismissed by film critics as being sentimental and without intellectual merit. But their popularity with audiences, who seek them out precisely because of their 'feel-good' qualities, tells a more favorable story. Now, for the first time, this popular movie genre has been examined scientifically.

Important factor in the development of dendritic cells identified

Dendritic cells are divided into Type 1 (DC1) and Type 2 (DC2) dendritic cells. Each type fulfills different functions: DC1 provide an immune response to bacteria and viruses, DC2 protect against fungal or parasitic infections. Researchers found that a particular group of proteins plays a major role in the development of Type 1 dendritic cells. This

Milestone for next-gen acceleration experiment

The future of particle acceleration has begun. Awake is a promising concept for a completely new method with which particles can be accelerated even over short distances. The basis for this is a plasma wave that accelerates electrons and thus brings them to high energies. A team now reports a breakthrough in this context. For the first time, they were able to precisely time the production of the...

Hippocampal maps predict context-dependent behavior

Successful navigation requires the ability to separate memories in a context-dependent manner. For example, to find lost keys, one must first remember whether the keys were left in the kitchen or the office. How does the human brain retrieve the contextual memories that drive behavior?

Shortage of DNA building blocks in the cell releases mitochondrial DNA

Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the release are not yet known, but some cardiac and neurodegenerative diseases as well as the ageing process are linked to the mitochondrial genome. Researchers have investigated the...

Researchers analyzed circulating currents inside gold nanoparticles

Researchers have developed a method that allows for simulation and visualization of magnetic-field-induced electron currents inside gold nanoparticles. The method facilitates accurate analysis of magnetic field effects inside complex nanostructures in nuclear magnetic resonance measurements and establishes quantitative criteria for aromaticity of nanoparticles.

New brain-like computing device simulates human learning

Researchers developed new synaptic transistors that can mimic the human brain's plasticity by simultaneously processing and storing data. After connecting transistors into a device, researchers conditioned it to associate light with pressure -- similar to how Pavlov's dog associated a bell with food.