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8 articles from EurekAlert
Better metric for thermoelectric materials means better design strategies
Researchers from Tokyo Metropolitan University have shown that a quantity known as "thermoelectric conductivity" is an effective measure for the dimensionality of newly developed thermoelectric nanomaterials. Studying films of semiconducting single-walled carbon nanotubes and atomically thin sheets of molybdenum sulfide and graphene, they found clear distinctions in how this number varies with...
Immune-stimulating drug before surgery shows promise in early-stage pancreatic cancer
Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.
Level of chromosomal abnormality in lung cancer may predict immunotherapy response
Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy - an abnormal number of chromosomes - tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021.
Mutant KRAS and p53 cooperate to drive pancreatic cancer metastasis
MD Anderson researchers have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact to promote metastasis and tumor growth. The findings point to a new therapeutic target for this deadly cancer.
New CAR T approach minimizes resistance, helps avoid relapse in non-Hodgkin's B-cell lymphoma
Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial led by researchers at the UCLA found using a bilateral attack achieves a more robust defense and helps avoid relapse.
Personalized cancer vaccine is safe, shows potential benefit against cancer
A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clinical trial presented during the virtual American Association for Cancer Research...
Resilience against replay attacks in computer systems
From power grids and telecommunications to water supply and financial systems, digital data controls the infrastructure systems on which society relies. These complex, multi-tier systems depend on layered communications to accomplish their tasks. Researchers from Italy has developed the first predictive control scheme that can help distributed networks with multiple agents not only identify these...
The impact of chemotherapy on immune cells in the tumor microenvironment
Research from Queen Mary University of London has revealed novel insights into the effects of chemotherapy on the tumour microenvironment (TME). The study, published today in Cancer Immunology Research, a journal of the American Association for Cancer Research, found that chemotherapy enhances the anti-tumour actions of immune cells within the TME and their ability to support immune responses...